ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028041 Adam15 10090 - 3:89338542-89349996 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029676 Adam15-001 89339640-89349996 protein_coding
  ENSMUST00000074582 Adam15-002 89339648-89349975 protein_coding
  ENSMUST00000107446 Adam15-003 89339644-89349959 protein_coding
  ENSMUST00000107448 Adam15-004 89339640-89349989 protein_coding
  ENSMUST00000134590 Adam15-008 89348518-89349107 processed_transcript
  ENSMUST00000134839 Adam15-006 89342732-89349974 retained_intron
  ENSMUST00000139705 Adam15-012 89339745-89340352 retained_intron
  ENSMUST00000144608 Adam15-009 89340074-89343679 retained_intron
  ENSMUST00000148068 Adam15-010 89339641-89341157 processed_transcript
  ENSMUST00000155295 Adam15-007 89346528-89349960 retained_intron
  ENSMUST00000155868 Adam15-011 89339915-89340919 retained_intron
  ENSMUST00000156250 Adam15-013 89339644-89340440 processed_transcript
  ENSMUST00000184651 Adam15-005 89338542-89349982 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000029676ENSMUST00000074582ENSMUST00000107448ENSMUST00000144608ENSMUST00000148068ENSMUST00000156250ENSMUST00000184651
Transcript ID C166 Tie2+ EC mES
ENSMUST00000029676 N/A 16.490±4.30 N/A
ENSMUST00000074582 10.576±3.33 40.576±27.51 2.022±0.00
ENSMUST00000107448 N/A 14.124±0.00 N/A
ENSMUST00000144608 N/A 39.125±0.60 N/A
ENSMUST00000148068 N/A N/A 23.476±0.00
ENSMUST00000156250 N/A 86.175±0.00 84.935±34.80
ENSMUST00000184651 N/A 3.215±0.00 4.819±2.82

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000402 CIL_000402_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001953 IEA negative regulation of cell-matrix adhesion
GO:0004222 IEA metalloendopeptidase activity
GO:0005178 IEA integrin binding
GO:0005515 IPI protein binding
GO:0006508 IEA proteolysis
GO:0007155 IEA cell adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008237 IEA metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0017124 IEA SH3 domain binding
GO:0030054 IEA cell junction
GO:0030308 IEA negative regulation of cell growth
GO:0030336 IEA negative regulation of cell migration
GO:0030574 IEA collagen catabolic process
GO:0031410 IEA cytoplasmic vesicle
GO:0042246 IEA tissue regeneration
GO:0042995 IEA cell projection
GO:0045087 IEA innate immune response
GO:0060317 IMP cardiac epithelial to mesenchymal transition
GO:0070062 IEA extracellular vesicular exosome
GO:0070528 IEA protein kinase C signaling
GO:1900121 IEA negative regulation of receptor binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089213 adam15 protein_coding Danio_rerio
ENSG00000143537 ADAM15 ADAM metallopeptidase domain 15 protein_coding Homo_sapiens

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