ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028068 Iqgap3 10090 + 3:88081971-88121048 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000071812 Iqgap3-001 88081971-88121048 protein_coding
  ENSMUST00000193861 Iqgap3-004 88086150-88087545 retained_intron
  ENSMUST00000193940 Iqgap3-003 88082020-88087552 retained_intron
  ENSMUST00000194440 Iqgap3-005 88105142-88121044 protein_coding
  ENSMUST00000194772 Iqgap3-006 88107116-88112164 retained_intron
  ENSMUST00000195465 Iqgap3-002 88082028-88108390 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000071812ENSMUST00000193940ENSMUST00000194440ENSMUST00000195465
Transcript ID C166 Tie2+ EC mES
ENSMUST00000071812 3.880±0.65 2.260±0.29 1.547±0.10
ENSMUST00000193940 N/A N/A 1.115±0.00
ENSMUST00000194440 N/A 1.611±1.11 1.374±0.37
ENSMUST00000195465 N/A 0.221±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000850 CIL_000850_0002 VISTA
CIL_0008JO CIL_0008JO_0002 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0000187 IMP activation of MAPK activity
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0005099 IEA Ras GTPase activator activity
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005737 IDA cytoplasm
GO:0005911 IDA cell-cell junction
GO:0007265 IMP Ras protein signal transduction
GO:0008361 IMP regulation of cell size
GO:0010628 IMP positive regulation of gene expression
GO:0010629 IMP negative regulation of gene expression
GO:0016328 IDA lateral plasma membrane
GO:0017016 IPI Ras GTPase binding
GO:0017048 IPI Rho GTPase binding
GO:0032320 IEA positive regulation of Ras GTPase activity
GO:0033601 IMP positive regulation of mammary gland epithelial cell proliferation
GO:0070371 IMP ERK1 and ERK2 cascade
GO:0070856 IEA myosin VI light chain binding
GO:0071310 IDA cellular response to organic substance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000183856 IQGAP3 IQ motif containing GTPase activating protein 3 protein_coding Homo_sapiens

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