ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029071 Dvl1 10090 + 4:155847402-155859303 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030948 Dvl1-001 155847402-155859303 protein_coding
  ENSMUST00000129450 Dvl1-004 155854572-155856232 retained_intron
  ENSMUST00000133184 Dvl1-005 155847566-155859303 retained_intron
  ENSMUST00000140529 Dvl1-006 155853410-155853951 processed_transcript
  ENSMUST00000141539 Dvl1-002 155847586-155859303 retained_intron
  ENSMUST00000143457 Dvl1-003 155847671-155859303 retained_intron
  ENSMUST00000156997 Dvl1-007 155847466-155859302 retained_intron
  ENSMUST00000168552 Dvl1-201 155847461-155858878 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000030948ENSMUST00000133184ENSMUST00000141539ENSMUST00000143457ENSMUST00000168552
Transcript ID C166 Tie2+ EC mES
ENSMUST00000030948 5.600±1.14 8.633±5.64 2.175±0.64
ENSMUST00000133184 N/A 1.275±0.84 5.273±3.99
ENSMUST00000141539 N/A 2.105±1.43 N/A
ENSMUST00000143457 3.025±0.00 N/A N/A
ENSMUST00000168552 8.434±0.96 5.966±0.05 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003D7 CIL_0003D7_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001505 IMP regulation of neurotransmitter levels
GO:0001932 IGI regulation of protein phosphorylation
GO:0001933 IGI negative regulation of protein phosphorylation
GO:0005109 IBA frizzled binding
GO:0005515 IPI protein binding
GO:0005874 IBA microtubule
GO:0005938 IBA cell cortex
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006469 IEA negative regulation of protein kinase activity
GO:0007269 IGI neurotransmitter secretion
GO:0007409 IDA axonogenesis
GO:0007411 IDA axon guidance
GO:0007528 IGI neuromuscular junction development
GO:0010976 IMP positive regulation of neuron projection development
GO:0015630 IDA microtubule cytoskeleton
GO:0016020 NAS membrane
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0016055 TAS Wnt signaling pathway
GO:0016328 IEA lateral plasma membrane
GO:0019899 IEA enzyme binding
GO:0019901 IBA protein kinase binding
GO:0021915 IEA neural tube development
GO:0022007 IGI convergent extension involved in neural plate elongation
GO:0030136 IDA clathrin-coated vesicle
GO:0030177 IEA positive regulation of Wnt signaling pathway
GO:0030424 IDA axon
GO:0030425 IBA dendrite
GO:0030426 IBA growth cone
GO:0031122 IDA cytoplasmic microtubule organization
GO:0031410 IEA cytoplasmic vesicle
GO:0032091 IEA negative regulation of protein binding
GO:0032436 IEA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034504 IEA protein localization to nucleus
GO:0035176 IMP social behavior
GO:0035372 IGI protein localization to microtubule
GO:0035556 IEA intracellular signal transduction
GO:0042802 IEA identical protein binding
GO:0043025 IBA neuronal cell body
GO:0043113 IGI receptor clustering
GO:0045202 IDA synapse
GO:0045893 IBA positive regulation of transcription, DNA-templated
GO:0048365 IBA Rac GTPase binding
GO:0048668 IDA collateral sprouting
GO:0048675 IDA axon extension
GO:0048813 IMP dendrite morphogenesis
GO:0050808 IGI synapse organization
GO:0060029 IGI convergent extension involved in organogenesis
GO:0060070 IGI canonical Wnt signaling pathway
GO:0060071 IDA Wnt signaling pathway, planar cell polarity pathway
GO:0060134 IMP prepulse inhibition
GO:0071340 IMP skeletal muscle acetylcholine-gated channel clustering
GO:0090103 IGI cochlea morphogenesis
GO:0090179 IGI planar cell polarity pathway involved in neural tube closure
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010515 dvl1a protein_coding Danio_rerio
ENSDARG00000055552 dvl1b protein_coding Danio_rerio
ENSDARG00000095919 si:ch73-236e11.2 protein_coding Danio_rerio
ENSG00000107404 DVL1 dishevelled segment polarity protein 1 protein_coding Homo_sapiens

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