ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: dishevelled segment polarity protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107404 DVL1 9606 - 1:1335276-1349350 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000378888 DVL1-004 1335276-1349350 protein_coding
  ENST00000378891 DVL1-001 1335276-1349112 protein_coding
  ENST00000472445 DVL1-005 1341770-1348955 retained_intron
  ENST00000610709 DVL1-201 1335279-1349135 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000378888ENST00000378891ENST00000610709
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000378888 N/A 2.398±1.18 N/A 2.867±0.00 2.607±1.35
ENST00000378891 13.268±4.28 14.444±4.68 13.486±0.00 14.328±0.00 8.329±6.22
ENST00000610709 19.366±4.37 3.930±0.92 N/A N/A 2.691±0.95

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005MO CIL_0005MO_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001505 ISS regulation of neurotransmitter levels
GO:0001932 IEA regulation of protein phosphorylation
GO:0001933 IEA negative regulation of protein phosphorylation
GO:0005109 IPI frizzled binding
GO:0005515 IPI:IEA protein binding
GO:0005874 IBA microtubule
GO:0005938 IBA cell cortex
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006469 IDA negative regulation of protein kinase activity
GO:0007269 ISS neurotransmitter secretion
GO:0007409 IEA axonogenesis
GO:0007411 IBA axon guidance
GO:0007528 ISS neuromuscular junction development
GO:0010976 IEA positive regulation of neuron projection development
GO:0015630 IEA microtubule cytoskeleton
GO:0016023 ISS cytoplasmic membrane-bounded vesicle
GO:0016328 IDA lateral plasma membrane
GO:0019899 IPI enzyme binding
GO:0019901 IPI protein kinase binding
GO:0021915 IEP neural tube development
GO:0022007 IEA convergent extension involved in neural plate elongation
GO:0030136 IBA clathrin-coated vesicle
GO:0030177 IDA positive regulation of Wnt signaling pathway
GO:0030424 IBA axon
GO:0030425 IBA dendrite
GO:0030426 IBA growth cone
GO:0031122 IEA cytoplasmic microtubule organization
GO:0031410 IDA cytoplasmic vesicle
GO:0032091 IDA negative regulation of protein binding
GO:0032436 IMP positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034504 IMP protein localization to nucleus
GO:0035176 IEA social behavior
GO:0035372 IEA protein localization to microtubule
GO:0035556 IEA intracellular signal transduction
GO:0042802 IPI identical protein binding
GO:0043025 IBA neuronal cell body
GO:0043113 ISS receptor clustering
GO:0045202 ISS synapse
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0048365 IBA Rac GTPase binding
GO:0048668 IBA collateral sprouting
GO:0048675 IBA axon extension
GO:0048813 ISS dendrite morphogenesis
GO:0050808 ISS synapse organization
GO:0060026 IBA convergent extension
GO:0060029 IEA convergent extension involved in organogenesis
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060071 IDA Wnt signaling pathway, planar cell polarity pathway
GO:0060134 IEA prepulse inhibition
GO:0071340 IBA skeletal muscle acetylcholine-gated channel clustering
GO:0090103 IBA cochlea morphogenesis
GO:0090179 IBA planar cell polarity pathway involved in neural tube closure
GO:0090263 IEA positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010515 dvl1a protein_coding Danio_rerio
ENSDARG00000055552 dvl1b protein_coding Danio_rerio
ENSDARG00000095919 si:ch73-236e11.2 protein_coding Danio_rerio
ENSMUSG00000029071 Dvl1 protein_coding Mus_musculus

Loading