ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029710 Ephb4 10090 + 5:137350109-137378669 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000061244 Ephb4-001 137350109-137374528 protein_coding
  ENSMUST00000111054 Ephb4-003 137350513-137374532 protein_coding
  ENSMUST00000111055 Ephb4-002 137350172-137374520 protein_coding
  ENSMUST00000144296 Ephb4-004 137350141-137378669 nonsense_mediated_decay
  ENSMUST00000166239 Ephb4-201 137350430-137374310 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000061244ENSMUST00000111054ENSMUST00000111055ENSMUST00000166239
Transcript ID C166 Tie2+ EC mES
ENSMUST00000061244 14.385±2.02 22.620±4.62 14.420±6.22
ENSMUST00000111054 N/A 12.282±0.00 2.478±0.00
ENSMUST00000111055 3.722±0.00 10.958±3.52 N/A
ENSMUST00000166239 6.018±0.55 11.574±0.00 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0002042 ISS cell migration involved in sprouting angiogenesis
GO:0003007 IMP heart morphogenesis
GO:0004714 ISS transmembrane receptor protein tyrosine kinase activity
GO:0005003 ISS ephrin receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005887 ISS integral component of plasma membrane
GO:0007155 ISS cell adhesion
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0046777 ISS protein autophosphorylation
GO:0048013 IGI ephrin receptor signaling pathway
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027112 ephb4b protein_coding Danio_rerio
ENSG00000196411 EPHB4 EPH receptor B4 protein_coding Homo_sapiens

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