ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: EPH receptor B4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196411 EPHB4 9606 - 7:100802565-100827521 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358173 EPHB4-001 100802565-100827499 protein_coding
  ENST00000360620 EPHB4-005 100802565-100827115 protein_coding
  ENST00000467515 EPHB4-008 100807365-100813339 retained_intron
  ENST00000477446 EPHB4-004 100813989-100827030 processed_transcript
  ENST00000478459 EPHB4-007 100806418-100814088 retained_intron
  ENST00000487222 EPHB4-002 100802568-100825526 retained_intron
  ENST00000489808 EPHB4-003 100817245-100827030 processed_transcript
  ENST00000492403 EPHB4-009 100805973-100807579 retained_intron
  ENST00000492878 EPHB4-006 100818551-100820482 retained_intron
  ENST00000616502 EPHB4-201 100802565-100827521 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000358173ENST00000360620ENST00000477446ENST00000478459ENST00000487222ENST00000616502
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000358173 17.102±1.17 23.086±8.84 58.872±0.00 41.650±30.28
ENST00000360620 N/A 29.035±7.61 N/A 25.570±14.93
ENST00000477446 N/A 36.351±0.00 N/A N/A
ENST00000478459 N/A 115.898±29.57 N/A 69.559±56.73
ENST00000487222 N/A N/A N/A 0.490±0.00
ENST00000616502 N/A N/A N/A 15.862±9.09

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 ISS angiogenesis
GO:0002042 IDA cell migration involved in sprouting angiogenesis
GO:0003007 ISS heart morphogenesis
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IDA transmembrane receptor protein tyrosine kinase activity
GO:0005003 IDA:IEA ephrin receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005887 IDA:IEA integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007155 IDA cell adhesion
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0046777 IDA protein autophosphorylation
GO:0048013 IDA:IEA ephrin receptor signaling pathway
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027112 ephb4b protein_coding Danio_rerio
ENSMUSG00000029710 Ephb4 protein_coding Mus_musculus

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