ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030341 Tnfrsf1a 10090 + 6:125349362-125362484 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032491 Tnfrsf1a-001 125349723-125362484 protein_coding
  ENSMUST00000125880 Tnfrsf1a-004 125357371-125361105 nonsense_mediated_decay
  ENSMUST00000130257 Tnfrsf1a-003 125349451-125357316 protein_coding
  ENSMUST00000131434 Tnfrsf1a-007 125349362-125350035 processed_transcript
  ENSMUST00000134803 Tnfrsf1a-005 125360427-125361874 retained_intron
  ENSMUST00000144524 Tnfrsf1a-006 125357765-125361778 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000032491
Transcript ID C166 Tie2+ EC mES
ENSMUST00000032491 102.722±15.35 30.394±7.50 7.602±2.96

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 ISS Golgi membrane
GO:0001666 IEA response to hypoxia
GO:0002020 IEA protease binding
GO:0005031 IMP tumor necrosis factor-activated receptor activity
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005739 IEA mitochondrion
GO:0005829 IEA cytosol
GO:0005886 TAS plasma membrane
GO:0006693 TAS prostaglandin metabolic process
GO:0006952 IMP defense response
GO:0006954 IMP inflammatory response
GO:0007166 IMP cell surface receptor signaling pathway
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009611 IEA response to wounding
GO:0009986 IDA cell surface
GO:0010628 IEA positive regulation of gene expression
GO:0010629 IEA negative regulation of gene expression
GO:0016021 IEA integral component of membrane
GO:0019221 IMP cytokine-mediated signaling pathway
GO:0030424 IEA axon
GO:0032403 IEA protein complex binding
GO:0032496 IEA response to lipopolysaccharide
GO:0032715 IEA negative regulation of interleukin-6 production
GO:0032760 IEA positive regulation of tumor necrosis factor production
GO:0033013 IEA tetrapyrrole metabolic process
GO:0033160 IEA positive regulation of protein import into nucleus, translocation
GO:0033209 IEA tumor necrosis factor-mediated signaling pathway
GO:0042511 IEA positive regulation of tyrosine phosphorylation of Stat1 protein
GO:0042742 IMP defense response to bacterium
GO:0042981 IEA regulation of apoptotic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043120 IEA tumor necrosis factor binding
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043200 IEA response to amino acid
GO:0043234 IEA protein complex
GO:0043235 ISO receptor complex
GO:0043279 IEA response to alkaloid
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0045121 IDA membrane raft
GO:0045202 IEA synapse
GO:0045471 IEA response to ethanol
GO:0045766 IEA positive regulation of angiogenesis
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0050728 IEA negative regulation of inflammatory response
GO:0050729 IMP positive regulation of inflammatory response
GO:0051291 IEA protein heterooligomerization
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071392 IEA cellular response to estradiol stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018569 tnfrsf1a protein_coding Danio_rerio
ENSDARG00000090478 TMEM238 (1 of 2) protein_coding Danio_rerio
ENSG00000067182 TNFRSF1A tumor necrosis factor receptor superfamily, member 1A protein_coding Homo_sapiens

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