ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030513 Pcsk6 10090 + 7:65861734-66050340 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000055576 Pcsk6-001 65862029-66050335 protein_coding
  ENSMUST00000098391 Pcsk6-002 65862136-66050334 protein_coding
  ENSMUST00000176199 Pcsk6-004 65861734-65952984 protein_coding
  ENSMUST00000176209 Pcsk6-003 65862432-66050340 protein_coding
  ENSMUST00000177272 Pcsk6-006 66038418-66043528 retained_intron
  ENSMUST00000177369 Pcsk6-005 65953012-65963193 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000055576ENSMUST00000098391ENSMUST00000176209
Transcript ID C166 Tie2+ EC mES
ENSMUST00000055576 3.661±2.25 0.443±0.02 0.157±0.02
ENSMUST00000098391 5.637±1.86 0.923±0.36 0.145±0.00
ENSMUST00000176209 4.243±1.67 0.500±0.00 0.226±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007CP CIL_0007CP_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004175 IEA endopeptidase activity
GO:0004252 IBA serine-type endopeptidase activity
GO:0005615 IBA extracellular space
GO:0005794 IBA Golgi apparatus
GO:0006508 IEA proteolysis
GO:0007354 IGI zygotic determination of anterior/posterior axis, embryo
GO:0007368 IGI determination of left/right symmetry
GO:0008201 IEA heparin binding
GO:0009100 IEA glycoprotein metabolic process
GO:0009986 IEA cell surface
GO:0016485 IBA protein processing
GO:0016486 IEA peptide hormone processing
GO:0031012 IEA extracellular matrix
GO:0032902 IEA nerve growth factor production
GO:0032940 IEA secretion by cell
GO:0048406 IEA nerve growth factor binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000140479 PCSK6 proprotein convertase subtilisin/kexin type 6 protein_coding Homo_sapiens

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