ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030557 Mef2a 10090 - 7:67231163-67372858 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032776 Mef2a-005 67234207-67372858 protein_coding
  ENSMUST00000072460 Mef2a-001 67234147-67372858 nonsense_mediated_decay
  ENSMUST00000076325 Mef2a-003 67234039-67372858 protein_coding
  ENSMUST00000107476 Mef2a-004 67231918-67372858 protein_coding
  ENSMUST00000133074 Mef2a-006 67251809-67372858 protein_coding
  ENSMUST00000135493 Mef2a-007 67232084-67316920 nonsense_mediated_decay
  ENSMUST00000144057 Mef2a-008 67349409-67372827 processed_transcript
  ENSMUST00000156690 Mef2a-002 67231163-67372858 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000032776ENSMUST00000107476ENSMUST00000133074ENSMUST00000156690
Transcript ID C166 Tie2+ EC mES
ENSMUST00000032776 8.534±0.00 11.090±1.77 N/A
ENSMUST00000107476 9.637±1.74 16.964±5.60 N/A
ENSMUST00000133074 N/A 41.895±11.65 N/A
ENSMUST00000156690 12.117±2.49 20.367±10.40 7.043±1.67

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000002 IMP mitochondrial genome maintenance
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000165 ISS MAPK cascade
GO:0000790 IDA nuclear chromatin
GO:0000977 ISS RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IC RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001085 IEA RNA polymerase II transcription factor binding
GO:0001105 IEA RNA polymerase II transcription coactivator activity
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006915 IEA apoptotic process
GO:0007399 IEA nervous system development
GO:0007507 IEA heart development
GO:0019901 IPI protein kinase binding
GO:0033613 IPI activating transcription factor binding
GO:0035035 ISS histone acetyltransferase binding
GO:0042826 ISS histone deacetylase binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046332 ISS SMAD binding
GO:0046982 IEA protein heterodimerization activity
GO:0046983 IEA protein dimerization activity
GO:0048311 IMP mitochondrion distribution
GO:0055005 IMP ventricular cardiac myofibril assembly
GO:0061337 IMP cardiac conduction
GO:0070375 ISS ERK5 cascade
GO:0071277 ISS cellular response to calcium ion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031756 mef2aa protein_coding Danio_rerio
ENSDARG00000057527 CABZ01014623.1 protein_coding Danio_rerio
ENSG00000068305 MEF2A myocyte enhancer factor 2A protein_coding Homo_sapiens

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