ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: myocyte enhancer factor 2A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000068305 MEF2A 9606 + 15:99565417-99716466 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000338042 MEF2A-201 99565928-99716422 protein_coding
  ENST00000354410 MEF2A-001 99565700-99716466 protein_coding
  ENST00000449277 MEF2A-004 99565990-99716406 protein_coding
  ENST00000557785 MEF2A-002 99565980-99713782 protein_coding
  ENST00000557942 MEF2A-005 99566087-99716424 protein_coding
  ENST00000558049 MEF2A-010 99565987-99645621 protein_coding
  ENST00000558812 MEF2A-003 99565928-99713324 protein_coding
  ENST00000558856 MEF2A-011 99565928-99657531 processed_transcript
  ENST00000558983 MEF2A-012 99565980-99671562 retained_intron
  ENST00000559036 MEF2A-006 99565969-99645831 retained_intron
  ENST00000559903 MEF2A-009 99566483-99645739 protein_coding
  ENST00000560493 MEF2A-008 99565417-99645761 protein_coding
  ENST00000561125 MEF2A-007 99706595-99715962 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000338042ENST00000354410ENST00000449277ENST00000557785ENST00000557942ENST00000558812
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000338042 N/A 4.546±1.32 N/A 9.593±0.00 5.122±2.23
ENST00000354410 N/A 1.891±0.50 N/A N/A 2.709±1.30
ENST00000449277 1.537±0.00 N/A 6.642±0.00 N/A 3.708±1.59
ENST00000557785 N/A 3.978±0.58 N/A N/A 5.784±2.57
ENST00000557942 0.664±0.00 3.356±0.21 N/A N/A 2.269±0.89
ENST00000558812 N/A N/A N/A N/A 0.499±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00079Q CIL_00079Q_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000002 ISS mitochondrial genome maintenance
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000165 IDA MAPK cascade
GO:0000790 ISS nuclear chromatin
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001105 IDA RNA polymerase II transcription coactivator activity
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006351 IDA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006915 IEA apoptotic process
GO:0007507 IEP heart development
GO:0007517 NAS muscle organ development
GO:0019901 IEA protein kinase binding
GO:0033613 IPI activating transcription factor binding
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035035 IPI histone acetyltransferase binding
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0042692 TAS muscle cell differentiation
GO:0042826 IPI histone deacetylase binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045087 TAS innate immune response
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046332 IPI SMAD binding
GO:0046982 IPI protein heterodimerization activity
GO:0046983 IEA protein dimerization activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048311 ISS mitochondrion distribution
GO:0048813 ISS dendrite morphogenesis
GO:0051149 TAS positive regulation of muscle cell differentiation
GO:0051403 TAS stress-activated MAPK cascade
GO:0055005 ISS ventricular cardiac myofibril assembly
GO:0061337 ISS cardiac conduction
GO:0070375 IMP ERK5 cascade
GO:0071277 IDA cellular response to calcium ion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031756 mef2aa protein_coding Danio_rerio
ENSDARG00000057527 CABZ01014623.1 protein_coding Danio_rerio
ENSMUSG00000030557 Mef2a protein_coding Mus_musculus

Loading