ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031537 Ikbkb 10090 - 8:22659212-22706589 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033939 Ikbkb-001 22659212-22706578 protein_coding
  ENSMUST00000063401 Ikbkb-011 22659768-22706589 protein_coding
  ENSMUST00000125314 Ikbkb-002 22659213-22706540 nonsense_mediated_decay
  ENSMUST00000126439 Ikbkb-006 22691840-22706574 retained_intron
  ENSMUST00000126496 Ikbkb-013 22668011-22669026 retained_intron
  ENSMUST00000131767 Ikbkb-014 22682757-22694065 protein_coding
  ENSMUST00000132279 Ikbkb-012 22660108-22661482 protein_coding
  ENSMUST00000135326 Ikbkb-003 22659213-22706534 nonsense_mediated_decay
  ENSMUST00000144583 Ikbkb-008 22681212-22706539 retained_intron
  ENSMUST00000144895 Ikbkb-007 22689131-22706559 retained_intron
  ENSMUST00000146212 Ikbkb-010 22660357-22706578 retained_intron
  ENSMUST00000149093 Ikbkb-005 22702008-22706563 retained_intron
  ENSMUST00000150214 Ikbkb-004 22702452-22706525 processed_transcript
  ENSMUST00000150259 Ikbkb-009 22675984-22706540 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000033939ENSMUST00000135326ENSMUST00000146212
Transcript ID C166 Tie2+ EC mES
ENSMUST00000033939 13.900±1.76 9.392±5.28 6.403±2.40
ENSMUST00000135326 N/A 2.956±0.00 N/A
ENSMUST00000146212 N/A 17.585±0.00 1.771±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001782 IMP B cell homeostasis
GO:0004672 IMP protein kinase activity
GO:0004702 TAS receptor signaling protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 TAS cytoplasm
GO:0007252 TAS I-kappaB phosphorylation
GO:0008384 IDA IkappaB kinase activity
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0010765 IGI positive regulation of sodium ion transport
GO:0019901 IEA protein kinase binding
GO:0023014 TAS signal transduction by phosphorylation
GO:0035631 IDA CD40 receptor complex
GO:0042501 IEA serine phosphorylation of STAT protein
GO:0042803 IEA protein homodimerization activity
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0051092 ISO positive regulation of NF-kappaB transcription factor activity
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0097110 ISO scaffold protein binding
GO:2001259 IGI positive regulation of cation channel activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079123 ikbkb protein_coding Danio_rerio
ENSG00000104365 IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta protein_coding Homo_sapiens

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