ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034218 Atm 10090 - 9:53439149-53536740 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000118282 Atm-001 53439149-53536740 protein_coding
  ENSMUST00000126598 Atm-005 53440105-53442560 retained_intron
  ENSMUST00000132249 Atm-004 53445375-53453617 protein_coding
  ENSMUST00000132403 Atm-002 53521847-53536673 retained_intron
  ENSMUST00000150244 Atm-003 53527194-53536608 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECENSMUST00000118282
Transcript ID C166 Tie2+ EC
ENSMUST00000118282 1.155±0.21 0.826±0.61

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000077 IMP DNA damage checkpoint
GO:0000723 IEA telomere maintenance
GO:0000781 IEA chromosome, telomeric region
GO:0001666 IEA response to hypoxia
GO:0001756 IGI somitogenesis
GO:0002331 IMP pre-B cell allelic exclusion
GO:0003677 IEA DNA binding
GO:0004672 IDA protein kinase activity
GO:0004674 ISS protein serine/threonine kinase activity
GO:0004677 IEA DNA-dependent protein kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 TAS nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005819 IDA spindle
GO:0006281 IMP DNA repair
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0006974 TAS cellular response to DNA damage stimulus
GO:0006975 IEA DNA damage induced protein phosphorylation
GO:0007050 IEA cell cycle arrest
GO:0007094 ISS mitotic spindle assembly checkpoint
GO:0007292 IMP female gamete generation
GO:0007420 IGI brain development
GO:0007507 IGI heart development
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010212 ISS response to ionizing radiation
GO:0016303 ISS 1-phosphatidylinositol-3-kinase activity
GO:0016572 IEA histone phosphorylation
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0030889 IEA negative regulation of B cell proliferation
GO:0031410 IEA cytoplasmic vesicle
GO:0032403 IEA protein complex binding
GO:0033151 IGI V(D)J recombination
GO:0035174 IEA histone serine kinase activity
GO:0035404 IEA histone-serine phosphorylation
GO:0036092 IEA phosphatidylinositol-3-phosphate biosynthetic process
GO:0042159 IGI lipoprotein catabolic process
GO:0043065 IEA positive regulation of apoptotic process
GO:0043517 IEA positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0043525 IGI positive regulation of neuron apoptotic process
GO:0046777 IEA protein autophosphorylation
GO:0046983 IEA protein dimerization activity
GO:0047485 ISS protein N-terminus binding
GO:0048599 IMP oocyte development
GO:0051402 IGI neuron apoptotic process
GO:0051726 IEA regulation of cell cycle
GO:0071044 ISS histone mRNA catabolic process
GO:0071480 IEA cellular response to gamma radiation
GO:0072434 IEA signal transduction involved in mitotic G2 DNA damage checkpoint
GO:0090399 IEA replicative senescence

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002385 atm protein_coding Danio_rerio
ENSG00000149311 ATM ATM serine/threonine kinase protein_coding Homo_sapiens

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