ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034460 Six4 10090 - 12:73099609-73113456 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043208 Six4-001 73099609-73113425 protein_coding
  ENSMUST00000175693 Six4-002 73103441-73113456 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; Tie2+ ECmESENSMUST00000043208ENSMUST00000175693
Transcript ID Tie2+ EC mES
ENSMUST00000043208 0.054±0.05 0.337±0.17
ENSMUST00000175693 0.006±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008MW CIL_0008MW_0002 VISTA
CIL_0006SM CIL_0006SM_0003 CGP
CIL_0006SL CIL_0006SL_0003 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IC nucleus
GO:0005737 IDA cytoplasm
GO:0007519 IGI skeletal muscle tissue development
GO:0008582 IGI regulation of synaptic growth at neuromuscular junction
GO:0008584 IMP male gonad development
GO:0010468 IGI regulation of gene expression
GO:0030238 IMP male sex determination
GO:0030910 IMP olfactory placode formation
GO:0032880 IGI regulation of protein localization
GO:0042472 IGI inner ear morphogenesis
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0043565 IDA sequence-specific DNA binding
GO:0043586 IMP tongue development
GO:0045214 IMP sarcomere organization
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046661 IMP male sex differentiation
GO:0048538 IGI thymus development
GO:0048699 IMP generation of neurons
GO:0048701 IGI embryonic cranial skeleton morphogenesis
GO:0048704 IGI embryonic skeletal system morphogenesis
GO:0048856 IGI anatomical structure development
GO:0050678 IMP regulation of epithelial cell proliferation
GO:0051451 IGI myoblast migration
GO:0060037 IMP pharyngeal system development
GO:0061055 IMP myotome development
GO:0061197 IMP fungiform papilla morphogenesis
GO:0061551 IMP trigeminal ganglion development
GO:0072075 IMP metanephric mesenchyme development
GO:0072095 IMP regulation of branch elongation involved in ureteric bud branching
GO:0072107 IMP positive regulation of ureteric bud formation
GO:0090190 IMP positive regulation of branching involved in ureteric bud morphogenesis
GO:0098528 IMP skeletal muscle fiber differentiation
GO:1902725 IMP negative regulation of satellite cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004695 six4a protein_coding Danio_rerio
ENSDARG00000031983 six4b protein_coding Danio_rerio
ENSG00000100625 SIX4 SIX homeobox 4 protein_coding Homo_sapiens

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