ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034656 Cacna1a 10090 + 8:84388440-84640246 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000121390 Cacna1a-001 84415364-84640246 protein_coding
  ENSMUST00000122053 Cacna1a-002 84415377-84640063 protein_coding
  ENSMUST00000126302 Cacna1a-006 84571797-84580462 retained_intron
  ENSMUST00000129620 Cacna1a-004 84547094-84554084 processed_transcript
  ENSMUST00000130507 Cacna1a-009 84638991-84639434 processed_transcript
  ENSMUST00000135382 Cacna1a-003 84388440-84519039 retained_intron
  ENSMUST00000141981 Cacna1a-008 84601444-84613042 retained_intron
  ENSMUST00000143215 Cacna1a-007 84601431-84612080 retained_intron
  ENSMUST00000144879 Cacna1a-005 84601470-84634524 retained_intron
  ENSMUST00000153691 Cacna1a-010 84601973-84617897 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000121390ENSMUST00000130507
Transcript ID C166 Tie2+ EC mES
ENSMUST00000121390 0.049±0.01 0.425±0.22 0.259±0.00
ENSMUST00000130507 1.737±0.32 N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0006KV CIL_0006KV_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000096 IMP sulfur amino acid metabolic process
GO:0003677 IEA DNA binding
GO:0005245 ISS voltage-gated calcium channel activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0005891 IDA voltage-gated calcium channel complex
GO:0006006 IMP glucose metabolic process
GO:0006816 IMP calcium ion transport
GO:0007204 ISS positive regulation of cytosolic calcium ion concentration
GO:0007214 IMP gamma-aminobutyric acid signaling pathway
GO:0007268 IMP synaptic transmission
GO:0007270 IMP neuron-neuron synaptic transmission
GO:0007274 IMP neuromuscular synaptic transmission
GO:0007416 IMP synapse assembly
GO:0007628 IMP adult walking behavior
GO:0008219 IEA cell death
GO:0008331 IMP high voltage-gated calcium channel activity
GO:0014051 IMP gamma-aminobutyric acid secretion
GO:0014056 IMP regulation of acetylcholine secretion, neurotransmission
GO:0016049 IMP cell growth
GO:0017156 IMP calcium ion-dependent exocytosis
GO:0017158 IDA regulation of calcium ion-dependent exocytosis
GO:0019226 IMP transmission of nerve impulse
GO:0019905 IEA syntaxin binding
GO:0021522 IMP spinal cord motor neuron differentiation
GO:0021590 IMP cerebellum maturation
GO:0021679 IMP cerebellar molecular layer development
GO:0021680 IMP cerebellar Purkinje cell layer development
GO:0021702 IMP cerebellar Purkinje cell differentiation
GO:0021750 IMP vestibular nucleus development
GO:0021953 IMP central nervous system neuron differentiation
GO:0030425 IDA dendrite
GO:0030644 IMP cellular chloride ion homeostasis
GO:0032353 IMP negative regulation of hormone biosynthetic process
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035249 IMP synaptic transmission, glutamatergic
GO:0042133 IMP neurotransmitter metabolic process
GO:0042391 IMP regulation of membrane potential
GO:0042445 IMP hormone metabolic process
GO:0042995 IEA cell projection
GO:0043025 IDA neuronal cell body
GO:0043113 IMP receptor clustering
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0046872 IEA metal ion binding
GO:0048265 IMP response to pain
GO:0048266 IMP behavioral response to pain
GO:0048791 IMP calcium ion-dependent exocytosis of neurotransmitter
GO:0048813 IMP dendrite morphogenesis
GO:0050770 IMP regulation of axonogenesis
GO:0050877 IMP neurological system process
GO:0050883 IMP musculoskeletal movement, spinal reflex action
GO:0050885 IMP neuromuscular process controlling balance
GO:0050905 IGI neuromuscular process
GO:0051899 IMP membrane depolarization
GO:0060024 IMP rhythmic synaptic transmission
GO:0070509 IBA calcium ion import
GO:0070588 IEA calcium ion transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006923 cacna1ab protein_coding Danio_rerio
ENSDARG00000037905 cacna1aa protein_coding Danio_rerio
ENSG00000141837 CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit protein_coding Homo_sapiens

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