ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000121390 Cacna1a-001 ENSMUSG00000034656 10090 + 8:84415364-84640246 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000121390
Transcript ID C166 Tie2+ EC mES
ENSMUST00000121390 0.049±0.01 0.425±0.22 0.259±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000096 IMP sulfur amino acid metabolic process
GO:0003677 IEA DNA binding
GO:0005245 ISS voltage-gated calcium channel activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0005891 IDA voltage-gated calcium channel complex
GO:0006006 IMP glucose metabolic process
GO:0006816 IMP calcium ion transport
GO:0007204 ISS positive regulation of cytosolic calcium ion concentration
GO:0007214 IMP gamma-aminobutyric acid signaling pathway
GO:0007268 IMP synaptic transmission
GO:0007270 IMP neuron-neuron synaptic transmission
GO:0007274 IMP neuromuscular synaptic transmission
GO:0007416 IMP synapse assembly
GO:0007628 IMP adult walking behavior
GO:0008219 IEA cell death
GO:0008331 IMP high voltage-gated calcium channel activity
GO:0014051 IMP gamma-aminobutyric acid secretion
GO:0014056 IMP regulation of acetylcholine secretion, neurotransmission
GO:0016049 IMP cell growth
GO:0017156 IMP calcium ion-dependent exocytosis
GO:0017158 IDA regulation of calcium ion-dependent exocytosis
GO:0019226 IMP transmission of nerve impulse
GO:0019905 IEA syntaxin binding
GO:0021522 IMP spinal cord motor neuron differentiation
GO:0021590 IMP cerebellum maturation
GO:0021679 IMP cerebellar molecular layer development
GO:0021680 IMP cerebellar Purkinje cell layer development
GO:0021702 IMP cerebellar Purkinje cell differentiation
GO:0021750 IMP vestibular nucleus development
GO:0021953 IMP central nervous system neuron differentiation
GO:0030425 IDA dendrite
GO:0030644 IMP cellular chloride ion homeostasis
GO:0032353 IMP negative regulation of hormone biosynthetic process
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035249 IMP synaptic transmission, glutamatergic
GO:0042133 IMP neurotransmitter metabolic process
GO:0042391 IMP regulation of membrane potential
GO:0042445 IMP hormone metabolic process
GO:0042995 IEA cell projection
GO:0043025 IDA neuronal cell body
GO:0043113 IMP receptor clustering
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0046872 IEA metal ion binding
GO:0048265 IMP response to pain
GO:0048266 IMP behavioral response to pain
GO:0048791 IMP calcium ion-dependent exocytosis of neurotransmitter
GO:0048813 IMP dendrite morphogenesis
GO:0050770 IMP regulation of axonogenesis
GO:0050877 IMP neurological system process
GO:0050883 IMP musculoskeletal movement, spinal reflex action
GO:0050885 IMP neuromuscular process controlling balance
GO:0050905 IGI neuromuscular process
GO:0051899 IMP membrane depolarization
GO:0060024 IMP rhythmic synaptic transmission
GO:0070509 IBA calcium ion import
GO:0070588 IEA calcium ion transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000150130 cacna1ab-202 protein_coding Danio_rerio 0 1321
ENSDART00000008139 cacna1ab-201 protein_coding Danio_rerio 0 1279
ENSDART00000089967 cacna1bb-201 protein_coding Danio_rerio 0 922
ENSDART00000132142 cacna1bb-001 protein_coding Danio_rerio 0 375
ENSDART00000089971 cacna1ea-201 protein_coding Danio_rerio 0 215
ENSDART00000132899 cacna1ea-002 protein_coding Danio_rerio 0 215
ENST00000277549 CACNA1B-201 protein_coding Homo_sapiens 0 1190
ENST00000277551 CACNA1B-002 protein_coding Homo_sapiens 0 1190
ENST00000357570 CACNA1E-201 protein_coding Homo_sapiens 0 359
ENST00000358338 CACNA1E-202 protein_coding Homo_sapiens 0 359
ENST00000360108 CACNA1E-006 protein_coding Homo_sapiens 0 359
ENST00000360228 CACNA1A-001 protein_coding Homo_sapiens 0 4564
ENST00000367567 CACNA1E-203 protein_coding Homo_sapiens 0 359
ENST00000367570 CACNA1E-001 protein_coding Homo_sapiens 0 359
ENST00000367573 CACNA1E-003 protein_coding Homo_sapiens 0 359
ENST00000371355 CACNA1B-202 protein_coding Homo_sapiens 0 1192
ENST00000371357 CACNA1B-005 protein_coding Homo_sapiens 0 1197
ENST00000371363 CACNA1B-003 protein_coding Homo_sapiens 0 1190
ENST00000371372 CACNA1B-001 protein_coding Homo_sapiens 0 1190
ENST00000524607 CACNA1E-004 protein_coding Homo_sapiens 0 359
ENST00000533229 CACNA1E-005 retained_intron Homo_sapiens 0 359
ENST00000573710 CACNA1A-002 protein_coding Homo_sapiens 0 4693
ENST00000573891 CACNA1A-004 nonsense_mediated_decay Homo_sapiens 0 582
ENST00000574822 CACNA1A-003 processed_transcript Homo_sapiens 0 1018
ENST00000585802 CACNA1A-012 protein_coding Homo_sapiens 0 2911
ENST00000587525 CACNA1A-013 protein_coding Homo_sapiens 0 2279
ENST00000590205 CACNA1A-009 retained_intron Homo_sapiens 0 327
ENST00000593160 CACNA1A-014 retained_intron Homo_sapiens 0 634
ENST00000593267 CACNA1A-010 retained_intron Homo_sapiens 0 429
ENST00000614285 CACNA1A-201 protein_coding Homo_sapiens 0 4536
ENST00000621551 CACNA1E-204 protein_coding Homo_sapiens 0 359
ENST00000621791 CACNA1E-002 protein_coding Homo_sapiens 0 359

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