ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035273 Hpse 10090 - 5:100679484-100719716 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045617 Hpse-001 100679484-100719716 protein_coding
  ENSMUST00000112908 Hpse-002 100684581-100719705 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000045617ENSMUST00000112908
Transcript ID C166 Tie2+ EC mES
ENSMUST00000045617 0.120±0.09 0.042±0.05 0.450±0.17
ENSMUST00000112908 0.031±0.01 N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00069P CIL_00069P_0002 CGP
CIL_0006JB CIL_0006JB_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005578 TAS proteinaceous extracellular matrix
GO:0005634 IDA nucleus
GO:0005764 IEA lysosome
GO:0005975 IEA carbohydrate metabolic process
GO:0007160 IEA cell-matrix adhesion
GO:0010575 IEA positive regulation vascular endothelial growth factor production
GO:0016020 IEA membrane
GO:0030194 IEA positive regulation of blood coagulation
GO:0030200 ISS heparan sulfate proteoglycan catabolic process
GO:0030305 ISO:ISS heparanase activity
GO:0033690 IDA positive regulation of osteoblast proliferation
GO:0042060 IDA wound healing
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0045121 IDA membrane raft
GO:0045545 IEA syndecan binding
GO:0046983 IEA protein dimerization activity
GO:0051797 IEA regulation of hair follicle development
GO:0051798 IDA positive regulation of hair follicle development
GO:0051897 IDA positive regulation of protein kinase B signaling
GO:0060055 IDA angiogenesis involved in wound healing
GO:0061042 IDA vascular wound healing

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063634 hpse protein_coding Danio_rerio
ENSG00000173083 HPSE heparanase protein_coding Homo_sapiens

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