ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036986 Pml 10090 - 9:58218076-58249786 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000085673 Pml-001 58218076-58249786 protein_coding
  ENSMUST00000114136 Pml-002 58218076-58249786 protein_coding
  ENSMUST00000124063 Pml-012 58219751-58249660 protein_coding
  ENSMUST00000124982 Pml-006 58247113-58249786 protein_coding
  ENSMUST00000126690 Pml-005 58218087-58249665 protein_coding
  ENSMUST00000130459 Pml-008 58247068-58249623 nonsense_mediated_decay
  ENSMUST00000135310 Pml-004 58218086-58249733 protein_coding
  ENSMUST00000138775 Pml-009 58230391-58233395 retained_intron
  ENSMUST00000148301 Pml-007 58229848-58249786 nonsense_mediated_decay
  ENSMUST00000148628 Pml-010 58218542-58233385 retained_intron
  ENSMUST00000153820 Pml-003 58221050-58249786 protein_coding
  ENSMUST00000154572 Pml-011 58220263-58230127 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000085673ENSMUST00000114136ENSMUST00000126690ENSMUST00000135310ENSMUST00000148628ENSMUST00000153820
Transcript ID C166 Tie2+ EC mES
ENSMUST00000085673 11.136±2.86 0.943±0.00 1.142±0.00
ENSMUST00000114136 4.224±0.46 2.928±0.90 3.769±0.30
ENSMUST00000126690 N/A 1.854±0.00 N/A
ENSMUST00000135310 2.223±0.00 N/A N/A
ENSMUST00000148628 N/A 2.486±1.51 N/A
ENSMUST00000153820 N/A 1.868±0.40 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 ISS response to hypoxia
GO:0001932 IMP regulation of protein phosphorylation
GO:0002230 IEA positive regulation of defense response to virus by host
GO:0003677 IEA DNA binding
GO:0003713 TAS transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 ISS nucleoplasm
GO:0005730 ISS nucleolus
GO:0005737 IEA cytoplasm
GO:0005768 IEA endosome
GO:0005829 IDA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006461 ISS protein complex assembly
GO:0006605 ISS protein targeting
GO:0006915 IEA apoptotic process
GO:0006919 IMP activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006977 IMP DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007050 IMP cell cycle arrest
GO:0007179 IMP transforming growth factor beta receptor signaling pathway
GO:0007182 IMP common-partner SMAD protein phosphorylation
GO:0007184 IMP SMAD protein import into nucleus
GO:0007569 IMP cell aging
GO:0008270 IEA zinc ion binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008631 IMP intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0009411 IMP response to UV
GO:0010332 IMP response to gamma radiation
GO:0010522 IMP regulation of calcium ion transport into cytosol
GO:0016032 IEA viral process
GO:0016363 IDA nuclear matrix
GO:0016525 ISS negative regulation of angiogenesis
GO:0016605 IMP PML body
GO:0030099 IMP myeloid cell differentiation
GO:0030308 ISS negative regulation of cell growth
GO:0030578 IDA PML body organization
GO:0031065 ISS positive regulation of histone deacetylation
GO:0031625 IEA ubiquitin protein ligase binding
GO:0031965 IEA nuclear membrane
GO:0032183 IEA SUMO binding
GO:0032211 IEA negative regulation of telomere maintenance via telomerase
GO:0032469 IMP endoplasmic reticulum calcium ion homeostasis
GO:0032922 IDA circadian regulation of gene expression
GO:0032938 IEA negative regulation of translation in response to oxidative stress
GO:0034097 IEA response to cytokine
GO:0042406 IDA extrinsic component of endoplasmic reticulum membrane
GO:0042752 IDA regulation of circadian rhythm
GO:0042771 IMP intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042803 IEA protein homodimerization activity
GO:0043153 IDA entrainment of circadian clock by photoperiod
GO:0043161 ISS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045087 IDA innate immune response
GO:0045165 IMP cell fate commitment
GO:0045343 IDA regulation of MHC class I biosynthetic process
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045930 IEA negative regulation of mitotic cell cycle
GO:0046332 IDA SMAD binding
GO:0046982 IEA protein heterodimerization activity
GO:0048384 IMP retinoic acid receptor signaling pathway
GO:0050821 IEA protein stabilization
GO:0050897 IEA cobalt ion binding
GO:0051457 ISO maintenance of protein location in nucleus
GO:0051607 IEA defense response to virus
GO:0051974 IEA negative regulation of telomerase activity
GO:0060058 IEA positive regulation of apoptotic process involved in mammary gland involution
GO:0060444 IMP branching involved in mammary gland duct morphogenesis
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071353 IDA cellular response to interleukin-4
GO:0072332 IMP intrinsic apoptotic signaling pathway by p53 class mediator
GO:0090398 ISS cellular senescence
GO:0097191 IMP extrinsic apoptotic signaling pathway
GO:1902187 IDA negative regulation of viral release from host cell
GO:2000059 IEA negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:2000779 ISS regulation of double-strand break repair
GO:2001235 IGI positive regulation of apoptotic signaling pathway
GO:2001238 IEA positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000140464 PML promyelocytic leukemia protein_coding Homo_sapiens

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