ANGIOGENES

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info
Description:
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSMUSG00000037509	Arhgef4	10090	+	1:34678188-34813309	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENSMUST00000047664		Arhgef4-001	34801704-34813309	protein_coding
	ENSMUST00000159021		Arhgef4-006	34750881-34807144	protein_coding
	ENSMUST00000159059		Arhgef4-007	34801722-34806698	retained_intron
	ENSMUST00000159747		Arhgef4-004	34678188-34812739	protein_coding
	ENSMUST00000160855		Arhgef4-003	34801741-34808911	nonsense_mediated_decay
	ENSMUST00000162599		Arhgef4-005	34732115-34811829	protein_coding
	ENSMUST00000162760		Arhgef4-002	34801721-34809218	retained_intron

Expression Patterns

No expression data.

Conserved Regions
Region ID	Sub-Region	Region Type
CIL_0001J9	CIL_0001J9_0002	CGP
CIL_0001J8	CIL_0001J8_0002	CGP

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0005085	ISS	guanyl-nucleotide exchange factor activity
GO:0005089	IEA	Rho guanyl-nucleotide exchange factor activity
GO:0005737	IEA	cytoplasm
GO:0019904	IEA	protein domain specific binding
GO:0030032	ISS	lamellipodium assembly
GO:0030676	ISS	Rac guanyl-nucleotide exchange factor activity
GO:0032321	IEA	positive regulation of Rho GTPase activity
GO:0032855	ISS	positive regulation of Rac GTPase activity
GO:0035556	IEA	intracellular signal transduction
GO:0043547	ISS	positive regulation of GTPase activity
GO:0046847	ISS	filopodium assembly

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000012914	arhgef4		protein_coding	Danio_rerio
ENSG00000136002	ARHGEF4	Rho guanine nucleotide exchange factor (GEF) 4	protein_coding	Homo_sapiens

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