ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037860 Aim2 10090 + 1:173350879-173466040 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000135370 Aim2-003 173455488-173456165 processed_transcript
  ENSMUST00000147604 Aim2-001 173350879-173466040 protein_coding
  ENSMUST00000151176 Aim2-002 173454971-173455595 protein_coding
  ENSMUST00000166137 Aim2-201 173455354-173466032 protein_coding
  ENSMUST00000173023 Aim2-005 173420598-173459719 protein_coding
  ENSMUST00000174263 Aim2-004 173419196-173427781 processed_transcript
  ENSMUST00000192575 Aim2-006 173455354-173462007 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000147604ENSMUST00000166137ENSMUST00000173023
Transcript ID C166 Tie2+ EC mES
ENSMUST00000147604 0.071±0.00 0.275±0.00 0.271±0.05
ENSMUST00000166137 0.396±0.18 0.468±0.00 0.780±0.14
ENSMUST00000173023 0.609±0.16 1.014±0.43 0.916±0.02

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002218 IDA activation of innate immune response
GO:0002230 IMP positive regulation of defense response to virus by host
GO:0003690 IDA double-stranded DNA binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006915 IEA apoptotic process
GO:0006954 IEA inflammatory response
GO:0032088 IEA negative regulation of NF-kappaB transcription factor activity
GO:0032461 IEA positive regulation of protein oligomerization
GO:0032731 IMP positive regulation of interleukin-1 beta production
GO:0033209 IEA tumor necrosis factor-mediated signaling pathway
GO:0035458 IDA cellular response to interferon-beta
GO:0035690 ISO cellular response to drug
GO:0042802 IPI identical protein binding
GO:0045087 IEA innate immune response
GO:0050702 ISO interleukin-1 beta secretion
GO:0050718 IGI positive regulation of interleukin-1 beta secretion
GO:0051092 IEA positive regulation of NF-kappaB transcription factor activity
GO:0070269 IDA pyroptosis
GO:0097169 IDA AIM2 inflammasome complex
GO:2001056 IMP positive regulation of cysteine-type endopeptidase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000163568 AIM2 absent in melanoma 2 protein_coding Homo_sapiens

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