ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042207 Kdm5b 10090 + 1:134560171-134635285 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047714 Kdm5b-001 134560171-134635285 protein_coding
  ENSMUST00000112197 Kdm5b-002 134560207-134606791 retained_intron
  ENSMUST00000112198 Kdm5b-003 134560192-134631522 protein_coding
  ENSMUST00000133725 Kdm5b-004 134621880-134625101 retained_intron
  ENSMUST00000186128 Kdm5b-005 134587977-134590686 retained_intron
  ENSMUST00000191572 Kdm5b-006 134622800-134627201 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000047714ENSMUST00000112198
Transcript ID C166 Tie2+ EC mES
ENSMUST00000047714 2.168±0.42 1.474±0.64 7.343±2.81
ENSMUST00000112198 7.953±1.65 2.852±0.91 6.827±2.10

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003714 IEA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0032453 IDA histone demethylase activity (H3-K4 specific)
GO:0034647 ISS histone demethylase activity (H3-trimethyl-K4 specific)
GO:0034648 ISS histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034720 ISS histone H3-K4 demethylation
GO:0034721 IEA histone H3-K4 demethylation, trimethyl-H3-K4-specific
GO:0042752 NAS regulation of circadian rhythm
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003098 kdm5bb protein_coding Danio_rerio
ENSDARG00000057093 kdm5ba protein_coding Danio_rerio
ENSG00000117139 KDM5B lysine (K)-specific demethylase 5B protein_coding Homo_sapiens

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