ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: lysine (K)-specific demethylase 5B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117139 KDM5B 9606 - 1:202724491-202809470 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000235790 KDM5B-002 202729905-202807299 protein_coding
  ENST00000367264 KDM5B-003 202727443-202808418 protein_coding
  ENST00000367265 KDM5B-001 202724491-202809470 protein_coding
  ENST00000456180 KDM5B-007 202753044-202758949 processed_transcript
  ENST00000467487 KDM5B-004 202774630-202807205 processed_transcript
  ENST00000470573 KDM5B-006 202773217-202806751 processed_transcript
  ENST00000472822 KDM5B-005 202729316-202736236 retained_intron
  ENST00000491153 KDM5B-009 202729901-202732141 retained_intron
  ENST00000498276 KDM5B-008 202745877-202746595 retained_intron
  ENST00000602511 KDM5B-010 202767031-202808125 nonsense_mediated_decay

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000235790ENST00000367264ENST00000367265ENST00000472822
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000235790 N/A 4.826±3.26 N/A N/A 3.375±1.56
ENST00000367264 1.120±0.49 12.158±4.14 2.967±0.00 9.155±0.00 9.205±4.39
ENST00000367265 N/A 1.257±0.00 N/A N/A 0.776±0.40
ENST00000472822 2.530±0.00 N/A N/A N/A 9.990±0.57

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0032453 IEA histone demethylase activity (H3-K4 specific)
GO:0034647 IDA histone demethylase activity (H3-trimethyl-K4 specific)
GO:0034648 IDA histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034720 IDA histone H3-K4 demethylation
GO:0034721 IDA histone H3-K4 demethylation, trimethyl-H3-K4-specific
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003098 kdm5bb protein_coding Danio_rerio
ENSDARG00000057093 kdm5ba protein_coding Danio_rerio
ENSMUSG00000042207 Kdm5b protein_coding Mus_musculus

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