ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042406 Atf4 10090 + 15:80255184-80257540 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000109605 Atf4-201 80255184-80257540 protein_coding

Mus musculus Ensembl GRCm38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000109605
Transcript ID C166 Tie2+ EC mES
ENSMUST00000109605 262.515±71.63 184.261±133.95 105.060±13.03

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003MS CIL_0003MS_0002 CGP
CIL_0005W7 CIL_0005W7_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IMP RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 IDA core promoter sequence-specific DNA binding
GO:0001077 IMP RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006094 IDA gluconeogenesis
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0007214 IEA gamma-aminobutyric acid signaling pathway
GO:0007623 IEP circadian rhythm
GO:0008022 IEA protein C-terminus binding
GO:0032590 IEA dendrite membrane
GO:0032922 IMP circadian regulation of gene expression
GO:0034399 IEA nuclear periphery
GO:0034976 IDA response to endoplasmic reticulum stress
GO:0036091 IEA positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0043005 IEA neuron projection
GO:0043267 IEA negative regulation of potassium ion transport
GO:0043525 IMP positive regulation of neuron apoptotic process
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:1903204 IEA negative regulation of oxidative stress-induced neuron death
GO:1990037 IEA Lewy body core
GO:1990440 IMP positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038141 atf4b protein_coding Danio_rerio
ENSDARG00000039515 atf4a protein_coding Danio_rerio
ENSG00000128272 ATF4 activating transcription factor 4 protein_coding Homo_sapiens

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