ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042626 Shc1 10090 + 3:89418443-89430027 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000039110 Shc1-001 89418443-89430015 protein_coding
  ENSMUST00000094378 Shc1-002 89421628-89429099 protein_coding
  ENSMUST00000107417 Shc1-003 89418614-89430015 protein_coding
  ENSMUST00000125036 Shc1-005 89418551-89426546 protein_coding
  ENSMUST00000128238 Shc1-007 89418594-89426702 protein_coding
  ENSMUST00000137793 Shc1-008 89421642-89426702 protein_coding
  ENSMUST00000146306 Shc1-009 89424526-89427358 processed_transcript
  ENSMUST00000153334 Shc1-004 89420633-89424043 retained_intron
  ENSMUST00000154791 Shc1-006 89418571-89424244 protein_coding
  ENSMUST00000191485 Shc1-201 89418551-89430027 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000094378ENSMUST00000107417ENSMUST00000191485
Transcript ID C166 Tie2+ EC mES
ENSMUST00000094378 36.921±4.62 N/A N/A
ENSMUST00000107417 58.724±7.19 12.647±4.48 N/A
ENSMUST00000191485 10.189±0.00 10.015±5.30 22.896±9.23

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 ISS MAPK cascade
GO:0000187 IMP:ISS activation of MAPK activity
GO:0001525 IMP angiogenesis
GO:0005158 IEA insulin receptor binding
GO:0005159 IEA insulin-like growth factor receptor binding
GO:0005168 IEA neurotrophin TRKA receptor binding
GO:0005515 IPI protein binding
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0005886 ISS plasma membrane
GO:0007173 IDA epidermal growth factor receptor signaling pathway
GO:0007507 IMP heart development
GO:0016337 IMP single organismal cell-cell adhesion
GO:0030971 IEA:IPI receptor tyrosine kinase binding
GO:0031532 IMP actin cytoskeleton reorganization
GO:0035556 IEA intracellular signal transduction
GO:0040008 IEA regulation of growth
GO:0042127 IMP regulation of cell proliferation
GO:0046875 IPI ephrin receptor binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075437 shc1 protein_coding Danio_rerio
ENSG00000160691 SHC1 SHC (Src homology 2 domain containing) transforming protein 1 protein_coding Homo_sapiens

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