ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000048960 Prex2 10090 + 1:10993465-11303681 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027056 Prex2-001 10993465-11303681 protein_coding
  ENSMUST00000187694 Prex2-004 11140691-11160596 retained_intron
  ENSMUST00000187745 Prex2-008 11258106-11298005 nonsense_mediated_decay
  ENSMUST00000188154 Prex2-006 11283993-11298204 nonsense_mediated_decay
  ENSMUST00000188189 Prex2-007 11258067-11297898 nonsense_mediated_decay
  ENSMUST00000189385 Prex2-005 11263963-11299594 nonsense_mediated_decay
  ENSMUST00000189822 Prex2-003 11098530-11150071 retained_intron
  ENSMUST00000190935 Prex2-002 10993518-10996601 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000027056ENSMUST00000189822
Transcript ID C166 Tie2+ EC mES
ENSMUST00000027056 17.655±3.94 15.557±5.51 1.012±0.09
ENSMUST00000189822 N/A 70.056±24.17 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005BU CIL_0005BU_0003 CGP
CIL_00087Z CIL_00087Z_0002 VISTA
CIL_0001SD CIL_0001SD_0003 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005886 IDA plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0008344 IMP adult locomotory behavior
GO:0014065 IMP phosphatidylinositol 3-kinase signaling
GO:0030675 IEA Rac GTPase activator activity
GO:0030676 IEA Rac guanyl-nucleotide exchange factor activity
GO:0032855 IEA positive regulation of Rac GTPase activity
GO:0048813 IMP dendrite morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071692 prex2 protein_coding Danio_rerio
ENSG00000046889 PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 protein_coding Homo_sapiens

Loading