ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000052085 Dock8 10090 + 19:24999529-25202432 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025831 Dock8-201 24999529-25202432 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000025831
Transcript ID C166 Tie2+ EC mES
ENSMUST00000025831 6.205±1.63 0.498±0.45 0.816±0.74

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0009AF CIL_0009AF_0002 VISTA
CIL_0000VS CIL_0000VS_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001771 IMP immunological synapse formation
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0007264 IEA small GTPase mediated signal transduction
GO:0016020 IEA membrane
GO:0031252 IDA cell leading edge
GO:0036336 IGI dendritic cell migration
GO:0043547 IEA positive regulation of GTPase activity
GO:0061485 IEA memory T cell proliferation
GO:0070233 IMP negative regulation of T cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055225 dock8 protein_coding Danio_rerio
ENSG00000107099 DOCK8 dedicator of cytokinesis 8 protein_coding Homo_sapiens

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