ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000052374 Actn2 10090 - 13:12269426-12340760 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000064204 Actn2-001 12269426-12340760 protein_coding
  ENSMUST00000110616 Actn2-002 12308219-12340732 protein_coding
  ENSMUST00000168193 Actn2-201 12269435-12340724 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000064204ENSMUST00000110616ENSMUST00000168193
Transcript ID C166 Tie2+ EC mES
ENSMUST00000064204 0.043±0.00 0.041±0.02 0.081±0.02
ENSMUST00000110616 N/A 0.173±0.05 0.018±0.00
ENSMUST00000168193 0.017±0.01 0.010±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008J8 CIL_0008J8_0002 VISTA
CIL_0008J9 CIL_0008J9_0002 VISTA
CIL_0008IY CIL_0008IY_0002 VISTA
CIL_00097Y CIL_00097Y_0002 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005865 TAS striated muscle thin filament
GO:0005925 IEA focal adhesion
GO:0006936 IDA muscle contraction
GO:0008092 IDA cytoskeletal protein binding
GO:0030017 IDA sarcomere
GO:0030018 IDA Z disc
GO:0030035 IEA microspike assembly
GO:0030175 IEA filopodium
GO:0030274 IPI LIM domain binding
GO:0030374 IDA ligand-dependent nuclear receptor transcription coactivator activity
GO:0030375 IDA thyroid hormone receptor coactivator activity
GO:0030674 TAS protein binding, bridging
GO:0030864 IEA cortical actin cytoskeleton
GO:0031432 IEA titin binding
GO:0042391 IEA regulation of membrane potential
GO:0042802 IEA identical protein binding
GO:0042803 TAS protein homodimerization activity
GO:0043267 IEA negative regulation of potassium ion transport
GO:0043268 IEA positive regulation of potassium ion transport
GO:0044325 IEA ion channel binding
GO:0046983 IEA protein dimerization activity
GO:0048041 IEA focal adhesion assembly
GO:0051015 IDA actin filament binding
GO:0051289 IEA protein homotetramerization
GO:0051373 IEA FATZ binding
GO:0070062 IEA extracellular vesicular exosome
GO:0070080 IEA titin Z domain binding
GO:1901017 IEA negative regulation of potassium ion transmembrane transporter activity
GO:1901018 IEA positive regulation of potassium ion transmembrane transporter activity
GO:2000009 IEA negative regulation of protein localization to cell surface
GO:2000273 IDA positive regulation of receptor activity
GO:2001141 IDA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071090 actn2b protein_coding Danio_rerio
ENSG00000077522 ACTN2 actinin, alpha 2 protein_coding Homo_sapiens

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