ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000053754 Chd8 10090 - 14:52198151-52257723 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000089752 Chd8-201 52198151-52237572 protein_coding
  ENSMUST00000122823 Chd8-008 52212800-52214236 retained_intron
  ENSMUST00000134329 Chd8-003 52203725-52207556 retained_intron
  ENSMUST00000136528 Chd8-011 52205741-52207703 retained_intron
  ENSMUST00000140603 Chd8-009 52211848-52213379 protein_coding
  ENSMUST00000145404 Chd8-010 52207836-52213023 retained_intron
  ENSMUST00000147309 Chd8-005 52199766-52204627 retained_intron
  ENSMUST00000147827 Chd8-004 52198476-52206097 retained_intron
  ENSMUST00000149694 Chd8-006 52222599-52227597 processed_transcript
  ENSMUST00000149975 Chd8-002 52198451-52237791 protein_coding
  ENSMUST00000155614 Chd8-007 52214957-52215926 retained_intron
  ENSMUST00000199135 Chd8-012 52254395-52257723 retained_intron
  ENSMUST00000200169 Chd8-001 52198151-52257723 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000089752ENSMUST00000149975ENSMUST00000200169
Transcript ID C166 Tie2+ EC mES
ENSMUST00000089752 N/A 2.687±1.62 3.208±0.33
ENSMUST00000149975 3.248±0.33 3.054±2.11 N/A
ENSMUST00000200169 5.664±1.86 3.942±0.53 3.132±1.12

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00078L CIL_00078L_0002 CGP
CIL_0003JD CIL_0003JD_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0002039 IPI p53 binding
GO:0003677 ISS DNA binding
GO:0003678 ISS DNA helicase activity
GO:0005515 IPI protein binding
GO:0005524 ISS ATP binding
GO:0005634 IDA nucleus
GO:0006200 IEA ATP catabolic process
GO:0006351 IEA transcription, DNA-templated
GO:0008013 ISS beta-catenin binding
GO:0008094 ISS DNA-dependent ATPase activity
GO:0030178 ISS negative regulation of Wnt signaling pathway
GO:0032508 IEA DNA duplex unwinding
GO:0035064 ISS methylated histone binding
GO:0042393 IDA histone binding
GO:0043044 ISS ATP-dependent chromatin remodeling
GO:0043066 IMP negative regulation of apoptotic process
GO:0043234 IEA protein complex
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0045945 ISS positive regulation of transcription from RNA polymerase III promoter
GO:0060070 ISS canonical Wnt signaling pathway
GO:0070016 IEA armadillo repeat domain binding
GO:0071339 ISS MLL1 complex
GO:2000270 IDA negative regulation of fibroblast apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075543 chd8 protein_coding Danio_rerio
ENSG00000100888 CHD8 chromodomain helicase DNA binding protein 8 protein_coding Homo_sapiens

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