ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000055737 Ghr 10090 - 15:3317760-3583492 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000069451 Ghr-005 3317760-3583230 protein_coding
  ENSMUST00000110697 Ghr-010 3327539-3471644 protein_coding
  ENSMUST00000110698 Ghr-002 3327525-3583188 protein_coding
  ENSMUST00000159508 Ghr-006 3346509-3583211 processed_transcript
  ENSMUST00000159912 Ghr-008 3543837-3583187 processed_transcript
  ENSMUST00000160343 Ghr-007 3341029-3583188 processed_transcript
  ENSMUST00000161180 Ghr-004 3384309-3583492 retained_intron
  ENSMUST00000161561 Ghr-001 3319009-3581842 protein_coding
  ENSMUST00000161770 Ghr-009 3333439-3582596 protein_coding
  ENSMUST00000162993 Ghr-003 3345227-3583212 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000069451ENSMUST00000110698ENSMUST00000161561
Transcript ID C166 Tie2+ EC mES
ENSMUST00000069451 26.225±5.38 4.069±0.58 3.642±1.04
ENSMUST00000110698 20.386±3.40 9.337±0.06 N/A
ENSMUST00000161561 9.808±1.23 2.629±1.73 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003B8 CIL_0003B8_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0000255 IMP allantoin metabolic process
GO:0004903 IDA growth hormone receptor activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005886 IDA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006101 IMP citrate metabolic process
GO:0006103 IMP 2-oxoglutarate metabolic process
GO:0006105 IMP succinate metabolic process
GO:0006107 IMP oxaloacetate metabolic process
GO:0006549 IMP isoleucine metabolic process
GO:0006573 IMP valine metabolic process
GO:0006600 IMP creatine metabolic process
GO:0006631 IMP fatty acid metabolic process
GO:0006897 IEA endocytosis
GO:0007259 IEA JAK-STAT cascade
GO:0009725 IEA response to hormone
GO:0009755 IEA hormone-mediated signaling pathway
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0017046 IPI peptide hormone binding
GO:0019221 IEA:IDA cytokine-mediated signaling pathway
GO:0019530 IMP taurine metabolic process
GO:0019838 IEA growth factor binding
GO:0019898 IDA extrinsic component of membrane
GO:0019901 IEA protein kinase binding
GO:0019903 IEA protein phosphatase binding
GO:0031623 IEA receptor internalization
GO:0032094 IEA response to food
GO:0032355 IEA response to estradiol
GO:0032869 IEA cellular response to insulin stimulus
GO:0032870 IEA cellular response to hormone stimulus
GO:0034097 IEA response to cytokine
GO:0040014 IDA regulation of multicellular organism growth
GO:0040018 IEA positive regulation of multicellular organism growth
GO:0042169 IEA SH2 domain binding
GO:0042803 IEA protein homodimerization activity
GO:0042976 IEA activation of Janus kinase activity
GO:0042977 IEA activation of JAK2 kinase activity
GO:0043025 IEA neuronal cell body
GO:0043235 IEA receptor complex
GO:0043278 IEA response to morphine
GO:0043434 IEA response to peptide hormone
GO:0044236 IEA multicellular organismal metabolic process
GO:0045597 IEA positive regulation of cell differentiation
GO:0046427 IEA positive regulation of JAK-STAT cascade
GO:0046449 IMP creatinine metabolic process
GO:0046898 IEA response to cycloheximide
GO:0048009 IEA insulin-like growth factor receptor signaling pathway
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0051384 IEA response to glucocorticoid
GO:0060351 IEA cartilage development involved in endochondral bone morphogenesis
GO:0060396 IEA growth hormone receptor signaling pathway
GO:0070195 IEA growth hormone receptor complex
GO:0070555 IEA response to interleukin-1
GO:1901215 IEA negative regulation of neuron death

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007671 ghrb protein_coding Danio_rerio
ENSDARG00000054771 ghra protein_coding Danio_rerio
ENSG00000112964 GHR growth hormone receptor protein_coding Homo_sapiens

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