ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000057230 Aak1 10090 + 6:86849517-86991864 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003710 Aak1-003 86850053-86991864 protein_coding
  ENSMUST00000089519 Aak1-001 86849517-86991864 protein_coding
  ENSMUST00000113668 Aak1-002 86849628-86951019 protein_coding
  ENSMUST00000156885 Aak1-004 86851185-86935507 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; Tie2+ ECENSMUST00000003710
Transcript ID Tie2+ EC
ENSMUST00000003710 0.734±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005112 ISS Notch binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005905 IEA coated pit
GO:0006468 ISS protein phosphorylation
GO:0006897 IEA endocytosis
GO:0019897 ISS extrinsic component of plasma membrane
GO:0030136 ISS clathrin-coated vesicle
GO:0031252 ISS cell leading edge
GO:0032880 ISS regulation of protein localization
GO:0035612 ISS AP-2 adaptor complex binding
GO:0043195 ISS terminal bouton
GO:0045747 ISS positive regulation of Notch signaling pathway
GO:0046777 ISS protein autophosphorylation
GO:0050821 ISS protein stabilization
GO:2000369 ISS regulation of clathrin-mediated endocytosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011855 aak1a protein_coding Danio_rerio
ENSDARG00000077686 aak1b protein_coding Danio_rerio
ENSG00000115977 AAK1 AP2 associated kinase 1 protein_coding Homo_sapiens

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