ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000059495 Arhgef12 10090 - 9:42963842-43105718 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000072767 Arhgef12-201 42963843-43105486 protein_coding
  ENSMUST00000165665 Arhgef12-202 42963842-43105718 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000072767ENSMUST00000165665
Transcript ID C166 Tie2+ EC mES
ENSMUST00000072767 9.755±2.03 11.741±5.84 6.704±0.43
ENSMUST00000165665 9.775±2.14 16.406±0.80 2.647±1.07

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003MJ CIL_0003MJ_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001664 IEA G-protein coupled receptor binding
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005096 IEA GTPase activator activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0016020 IEA membrane
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030532 ARHGEF12 (1 of 2) protein_coding Danio_rerio
ENSG00000196914 ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 protein_coding Homo_sapiens

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