ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000061393 Acvr2b 10090 + 9:119402444-119433501 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035093 Acvr2b-201 119402444-119433501 protein_coding
  ENSMUST00000165044 Acvr2b-202 119402501-119433501 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000035093ENSMUST00000165044
Transcript ID C166 Tie2+ EC mES
ENSMUST00000035093 0.224±0.00 0.442±0.00 N/A
ENSMUST00000165044 0.795±0.27 0.530±0.00 3.930±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008BE CIL_0008BE_0002 VISTA
CIL_0005W6 CIL_0005W6_0002 CGP
CIL_0005W0 CIL_0005W0_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 IGI skeletal system development
GO:0001702 IGI gastrulation with mouth forming second
GO:0001822 IGI kidney development
GO:0001946 IMP lymphangiogenesis
GO:0001974 IMP blood vessel remodeling
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004702 IEA receptor signaling protein serine/threonine kinase activity
GO:0004712 IDA protein serine/threonine/tyrosine kinase activity
GO:0005024 IEA transforming growth factor beta-activated receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0007165 IEA signal transduction
GO:0007368 IGI determination of left/right symmetry
GO:0007389 IGI pattern specification process
GO:0007498 IGI mesoderm development
GO:0007507 IGI heart development
GO:0009749 IGI response to glucose
GO:0009791 IGI post-embryonic development
GO:0009952 IGI anterior/posterior pattern specification
GO:0009966 IDA regulation of signal transduction
GO:0016021 IEA integral component of membrane
GO:0019838 IPI growth factor binding
GO:0023014 IEA signal transduction by phosphorylation
GO:0030073 IGI insulin secretion
GO:0030324 IGI lung development
GO:0030501 IEA positive regulation of bone mineralization
GO:0030509 IEA BMP signaling pathway
GO:0031016 IGI pancreas development
GO:0032147 IDA activation of protein kinase activity
GO:0032927 IEA positive regulation of activin receptor signaling pathway
GO:0034711 IEA inhibin binding
GO:0035265 IGI organ growth
GO:0042475 IMP odontogenesis of dentin-containing tooth
GO:0043234 ISO protein complex
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0046872 IEA metal ion binding
GO:0048185 IPI activin binding
GO:0048617 IMP embryonic foregut morphogenesis
GO:0048705 IGI skeletal system morphogenesis
GO:0060021 IGI palate development
GO:0060836 IMP lymphatic endothelial cell differentiation
GO:0060840 IMP artery development
GO:0060841 IMP venous blood vessel development
GO:0061298 IMP retina vasculature development in camera-type eye

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044422 acvr2b protein_coding Danio_rerio
ENSG00000114739 ACVR2B activin A receptor, type IIB protein_coding Homo_sapiens

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