ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000063358 Mapk1 10090 + 16:16983382-17047453 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023462 Mapk1-002 16983382-17044749 protein_coding
  ENSMUST00000069107 Mapk1-001 16983382-17047453 protein_coding
  ENSMUST00000115731 Mapk1-003 16983567-17039040 protein_coding
  ENSMUST00000128958 Mapk1-008 17035338-17038705 processed_transcript
  ENSMUST00000129477 Mapk1-006 17026366-17043863 protein_coding
  ENSMUST00000138165 Mapk1-005 17026026-17027194 retained_intron
  ENSMUST00000138413 Mapk1-004 17018413-17024055 retained_intron
  ENSMUST00000145409 Mapk1-007 17035549-17044210 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000023462ENSMUST00000069107ENSMUST00000115731
Transcript ID C166 Tie2+ EC mES
ENSMUST00000023462 46.772±2.73 13.187±2.97 N/A
ENSMUST00000069107 31.558±2.98 11.936±2.06 15.961±1.77
ENSMUST00000115731 24.287±3.32 13.358±0.04 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008PT CIL_0008PT_0002 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IDA MAPK cascade
GO:0000189 IEA MAPK import into nucleus
GO:0001784 IMP phosphotyrosine binding
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004707 IMP MAP kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005769 TAS early endosome
GO:0005770 TAS late endosome
GO:0005794 TAS Golgi apparatus
GO:0005829 IDA cytosol
GO:0005856 TAS cytoskeleton
GO:0005901 TAS caveola
GO:0005925 TAS focal adhesion
GO:0006351 NAS transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007049 IEA cell cycle
GO:0007165 IEA signal transduction
GO:0008134 IEA transcription factor binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008353 IDA RNA polymerase II carboxy-terminal domain kinase activity
GO:0009636 IEA response to toxic substance
GO:0009887 IDA organ morphogenesis
GO:0010800 IEA positive regulation of peptidyl-threonine phosphorylation
GO:0015630 IEA microtubule cytoskeleton
GO:0016301 IDA kinase activity
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0018107 IDA peptidyl-threonine phosphorylation
GO:0019233 IEA sensory perception of pain
GO:0019858 IDA cytosine metabolic process
GO:0019901 IEA protein kinase binding
GO:0019902 IEA phosphatase binding
GO:0030335 IEA positive regulation of cell migration
GO:0030424 IEA axon
GO:0031143 IDA pseudopodium
GO:0031435 IEA mitogen-activated protein kinase kinase kinase binding
GO:0031647 ISS regulation of protein stability
GO:0031663 IDA lipopolysaccharide-mediated signaling pathway
GO:0032496 IDA response to lipopolysaccharide
GO:0032839 IEA dendrite cytoplasm
GO:0032872 TAS regulation of stress-activated MAPK cascade
GO:0033598 IDA mammary gland epithelial cell proliferation
GO:0035556 IEA intracellular signal transduction
GO:0038127 IEA ERBB signaling pathway
GO:0043204 IEA perikaryon
GO:0043234 IEA protein complex
GO:0043330 IDA response to exogenous dsRNA
GO:0043627 IEA response to estrogen
GO:0045596 IGI negative regulation of cell differentiation
GO:0045727 IEA positive regulation of translation
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0050852 IDA T cell receptor signaling pathway
GO:0050853 IDA B cell receptor signaling pathway
GO:0051090 NAS regulation of sequence-specific DNA binding transcription factor activity
GO:0051493 TAS regulation of cytoskeleton organization
GO:0060716 IMP labyrinthine layer blood vessel development
GO:0070062 IEA extracellular vesicular exosome
GO:0070371 IEA ERK1 and ERK2 cascade
GO:0070849 ISS response to epidermal growth factor
GO:0071310 IEA cellular response to organic substance
GO:0072584 TAS caveolin-mediated endocytosis
GO:0072686 ISS mitotic spindle
GO:0090170 TAS regulation of Golgi inheritance
GO:0097011 IDA cellular response to granulocyte macrophage colony-stimulating factor stimulus
GO:2000641 TAS regulation of early endosome to late endosome transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027552 mapk1 protein_coding Danio_rerio
ENSG00000100030 MAPK1 mitogen-activated protein kinase 1 protein_coding Homo_sapiens

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