ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000075318 Scn2a1 10090 + 2:65620771-65767447 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028377 Scn2a1-001 65620771-65767447 protein_coding
  ENSMUST00000100067 Scn2a1-201 65670445-65767447 protein_coding
  ENSMUST00000138368 Scn2a1-003 65682280-65683866 retained_intron
  ENSMUST00000144254 Scn2a1-004 65620771-65690175 protein_coding
  ENSMUST00000200829 Scn2a1-002 65668765-65765055 protein_coding
  ENSMUST00000201378 Scn2a1-005 65620811-65623264 retained_intron
  ENSMUST00000202162 Scn2a1-008 65717576-65728392 nonsense_mediated_decay
  ENSMUST00000202508 Scn2a1-007 65717553-65728441 nonsense_mediated_decay
  ENSMUST00000202653 Scn2a1-006 65668686-65671797 retained_intron

Mus musculus Ensembl GRCm38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000028377ENSMUST00000100067ENSMUST00000200829ENSMUST00000201378ENSMUST00000202653
Transcript ID C166 Tie2+ EC mES
ENSMUST00000028377 N/A 0.104±0.00 N/A
ENSMUST00000100067 0.236±0.11 0.048±0.04 0.028±0.01
ENSMUST00000200829 0.167±0.06 0.043±0.00 0.006±0.00
ENSMUST00000201378 N/A 0.060±0.01 N/A
ENSMUST00000202653 1.354±0.31 0.098±0.07 0.201±0.01

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0006CO CIL_0006CO_0002 CGP
CIL_0006CJ CIL_0006CJ_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001518 TAS voltage-gated sodium channel complex
GO:0005248 IDA voltage-gated sodium channel activity
GO:0006814 IDA sodium ion transport
GO:0007399 IMP nervous system development
GO:0008627 IMP intrinsic apoptotic signaling pathway in response to osmotic stress
GO:0014704 IDA intercalated disc
GO:0016020 IDA membrane
GO:0019228 IBA neuronal action potential
GO:0030315 IDA T-tubule
GO:0030424 IDA axon
GO:0033270 IDA paranode region of axon
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0051402 IMP neuron apoptotic process
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062744 scn1lab protein_coding Danio_rerio
ENSG00000136531 SCN2A sodium channel, voltage-gated, type II, alpha subunit protein_coding Homo_sapiens

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