ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: sodium channel, voltage-gated, type II, alpha subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136531 SCN2A 9606 + 2:165239402-165392308 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000283256 SCN2A-001 165294031-165392053 protein_coding
  ENST00000375427 SCN2A-002 165295773-165390029 protein_coding
  ENST00000375437 SCN2A-201 165239402-165392308 protein_coding
  ENST00000424833 SCN2A-003 165239402-165315598 protein_coding
  ENST00000480032 SCN2A-005 165294044-165381003 retained_intron
  ENST00000486878 SCN2A-004 165308666-165310745 retained_intron

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHUVECENST00000283256ENST00000375427ENST00000424833ENST00000480032
Transcript ID BECs HAoEC HUVEC
ENST00000283256 N/A 0.004±0.00 0.003±0.00
ENST00000375427 0.023±0.00 0.009±0.00 0.004±0.00
ENST00000424833 N/A 0.025±0.01 0.011±0.00
ENST00000480032 N/A 0.011±0.00 0.004±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0006CO CIL_0006CO_0001 CGP
CIL_0006CJ CIL_0006CJ_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001518 IEA voltage-gated sodium channel complex
GO:0005216 IEA ion channel activity
GO:0005248 ISS:IEA voltage-gated sodium channel activity
GO:0005515 IEA protein binding
GO:0005886 IBA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006811 IEA ion transport
GO:0006814 TAS:IEA sodium ion transport
GO:0007399 IEA nervous system development
GO:0008627 IEA intrinsic apoptotic signaling pathway in response to osmotic stress
GO:0014704 IEA intercalated disc
GO:0016020 IEA membrane
GO:0019228 IBA neuronal action potential
GO:0030315 IEA T-tubule
GO:0030424 TAS axon
GO:0031226 ISS intrinsic component of plasma membrane
GO:0033268 ISS node of Ranvier
GO:0033270 IEA paranode region of axon
GO:0034706 ISS sodium channel complex
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA:ISS sodium ion transmembrane transport
GO:0042552 ISS myelination
GO:0051402 IEA neuron apoptotic process
GO:0055085 IEA transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062744 scn1lab protein_coding Danio_rerio
ENSMUSG00000075318 Scn2a1 protein_coding Mus_musculus

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