ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info

Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000034713 Ldlr-201 ENSMUSG00000032193 10090 + 9:21723576-21749916 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000034713
Transcript ID C166 Tie2+ EC mES
ENSMUST00000034713 27.704±6.51 6.224±3.93 13.260±9.02

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001948 IEA glycoprotein binding
GO:0005041 IDA low-density lipoprotein receptor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005764 ISS lysosome
GO:0005768 IDA endosome
GO:0005769 ISS early endosome
GO:0005770 ISS late endosome
GO:0005794 ISS Golgi apparatus
GO:0005886 TAS plasma membrane
GO:0005905 IEA coated pit
GO:0006629 IGI lipid metabolic process
GO:0006898 IDA receptor-mediated endocytosis
GO:0008203 IMP cholesterol metabolic process
GO:0009897 IEA external side of plasma membrane
GO:0009986 ISS cell surface
GO:0010867 IMP positive regulation of triglyceride biosynthetic process
GO:0010899 IMP regulation of phosphatidylcholine catabolic process
GO:0015914 IMP phospholipid transport
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030169 IDA low-density lipoprotein particle binding
GO:0030229 IDA very-low-density lipoprotein particle receptor activity
GO:0030299 IEA intestinal cholesterol absorption
GO:0030301 IMP cholesterol transport
GO:0034362 IEA low-density lipoprotein particle
GO:0034383 IMP low-density lipoprotein particle clearance
GO:0042157 IGI lipoprotein metabolic process
GO:0042159 IDA lipoprotein catabolic process
GO:0042632 IGI cholesterol homeostasis
GO:0043235 ISO receptor complex
GO:0070508 IMP cholesterol import
GO:2000188 IMP regulation of cholesterol homeostasis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000252444 LDLR-004 protein_coding Homo_sapiens 0 1890
ENST00000557933 LDLR-012 protein_coding Homo_sapiens 0 1711
ENST00000558013 LDLR-002 protein_coding Homo_sapiens 0 1857
ENST00000558518 LDLR-003 protein_coding Homo_sapiens 0 1890

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