ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: cyclin D1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000227507 CCND1-001 ENSG00000110092 9606 + 11:69641087-69654474 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000227507
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000227507 24.525±4.35 61.617±40.05 2.276±0.00 170.877±0.00 67.206±59.35

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000079 IEA regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000278 TAS mitotic cell cycle
GO:0000307 IDA cyclin-dependent protein kinase holoenzyme complex
GO:0000320 IEA re-entry into mitotic cell cycle
GO:0001889 IEA liver development
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0003714 IDA transcription corepressor activity
GO:0004672 IEA protein kinase activity
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005923 IEA tight junction
GO:0006351 IEA transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007219 TAS Notch signaling pathway
GO:0007595 IEA lactation
GO:0008134 IPI transcription factor binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0010033 IEA response to organic substance
GO:0010039 IEA response to iron ion
GO:0010165 IEA response to X-ray
GO:0010243 IEA response to organonitrogen compound
GO:0010971 IDA positive regulation of G2/M transition of mitotic cell cycle
GO:0014070 IEA response to organic cyclic compound
GO:0016020 IEA membrane
GO:0016055 IEA Wnt signaling pathway
GO:0016301 IEA kinase activity
GO:0016538 IEA cyclin-dependent protein serine/threonine kinase regulator activity
GO:0017053 IDA transcriptional repressor complex
GO:0019899 IPI enzyme binding
GO:0019901 IPI:IEA protein kinase binding
GO:0030178 IEA negative regulation of Wnt signaling pathway
GO:0030857 IEA negative regulation of epithelial cell differentiation
GO:0030968 IEA endoplasmic reticulum unfolded protein response
GO:0031100 IEA organ regeneration
GO:0031571 IDA mitotic G1 DNA damage checkpoint
GO:0032026 IEA response to magnesium ion
GO:0032403 IEA protein complex binding
GO:0033197 IEA response to vitamin E
GO:0033327 IEA Leydig cell differentiation
GO:0033598 IEA mammary gland epithelial cell proliferation
GO:0033601 IEA positive regulation of mammary gland epithelial cell proliferation
GO:0042493 IEP response to drug
GO:0042826 IPI histone deacetylase binding
GO:0043627 IEA response to estrogen
GO:0045444 IEA fat cell differentiation
GO:0045471 IEA response to ethanol
GO:0045737 IDA positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0048545 IEA response to steroid hormone
GO:0051301 IEA cell division
GO:0051384 IEA response to glucocorticoid
GO:0051412 IEA response to corticosterone
GO:0051592 IEA response to calcium ion
GO:0051726 IEA regulation of cell cycle
GO:0060070 IEA canonical Wnt signaling pathway
GO:0060749 IEA mammary gland alveolus development
GO:0070064 IDA proline-rich region binding
GO:0070141 IDA response to UV-A
GO:0071157 IDA negative regulation of cell cycle arrest
GO:0071310 IEA cellular response to organic substance
GO:2000045 IEA regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000093962 Ccnd1-001 protein_coding Mus_musculus 0 1450
ENSMUST00000135985 Ccnd1-002 retained_intron Mus_musculus 0 547

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