ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: notch 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000256646 NOTCH2-001 ENSG00000134250 9606 - 1:119911553-120069626 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000256646
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000256646 0.542±0.22 12.211±3.29 0.125±0.00 1.539±0.00 6.225±4.38

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000139 TAS Golgi membrane
GO:0001701 IEA in utero embryonic development
GO:0001709 TAS cell fate determination
GO:0001890 IEA placenta development
GO:0002011 IEA morphogenesis of an epithelial sheet
GO:0002437 IEA inflammatory response to antigenic stimulus
GO:0003184 IMP pulmonary valve morphogenesis
GO:0004872 NAS receptor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0005929 IEA cilium
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006915 TAS apoptotic process
GO:0006959 IEA humoral immune response
GO:0007050 IDA cell cycle arrest
GO:0007219 TAS:IEA Notch signaling pathway
GO:0007220 TAS Notch receptor processing
GO:0007275 NAS:IEA multicellular organismal development
GO:0007368 IEA determination of left/right symmetry
GO:0007399 NAS nervous system development
GO:0008284 IEA positive regulation of cell proliferation
GO:0008285 IDA negative regulation of cell proliferation
GO:0009887 IEP organ morphogenesis
GO:0009986 IDA cell surface
GO:0010467 TAS gene expression
GO:0016020 IDA:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016049 IDA cell growth
GO:0019827 TAS stem cell maintenance
GO:0030097 TAS hemopoiesis
GO:0030154 IEA cell differentiation
GO:0030326 IEA embryonic limb morphogenesis
GO:0030513 IEA positive regulation of BMP signaling pathway
GO:0030522 TAS intracellular receptor signaling pathway
GO:0038049 TAS ligand-activated RNA polymerase II transcription factor binding transcription factor activity
GO:0042742 IEA defense response to bacterium
GO:0043011 IEA myeloid dendritic cell differentiation
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0043235 IDA receptor complex
GO:0046579 IDA positive regulation of Ras protein signal transduction
GO:0046849 IMP bone remodeling
GO:0050793 IEA regulation of developmental process
GO:0060413 IMP atrial septum morphogenesis
GO:0060674 IEA placenta blood vessel development
GO:0061073 IEA ciliary body morphogenesis
GO:0061314 IC Notch signaling involved in heart development
GO:0072602 IEA interleukin-4 secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000079812 Notch2-001 protein_coding Mus_musculus 0 8434
ENSDART00000032967 notch2-201 protein_coding Danio_rerio 0 344
ENSDART00000123104 notch2-001 protein_coding Danio_rerio 0 344

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