ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: sodium channel, voltage-gated, type I, beta subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000262631 SCN1B-001 ENSG00000105711 9606 + 19:35030684-35040448 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000262631
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000262631 30.178±17.12 7.428±3.19 9.103±0.00 9.278±7.83

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001518 IDA voltage-gated sodium channel complex
GO:0005248 IDA voltage-gated sodium channel activity
GO:0005576 IEA extracellular region
GO:0007155 IEA cell adhesion
GO:0007268 TAS synaptic transmission
GO:0007411 ISS axon guidance
GO:0010765 IDA positive regulation of sodium ion transport
GO:0010976 ISS positive regulation of neuron projection development
GO:0014704 ISS intercalated disc
GO:0017080 IDA sodium channel regulator activity
GO:0019227 ISS neuronal action potential propagation
GO:0019871 ISS sodium channel inhibitor activity
GO:0021966 ISS corticospinal neuron axon guidance
GO:0030315 ISS T-tubule
GO:0033268 ISS node of Ranvier
GO:0035725 IMP sodium ion transmembrane transport
GO:0040011 ISS locomotion
GO:0051899 IDA membrane depolarization
GO:0060048 IMP cardiac muscle contraction
GO:0060307 ISS regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060371 IMP regulation of atrial cardiac muscle cell membrane depolarization
GO:0061337 ISS cardiac conduction
GO:0086002 IMP cardiac muscle cell action potential involved in contraction
GO:0086006 IMP voltage-gated sodium channel activity involved in cardiac muscle cell action potential
GO:0086012 ISS membrane depolarization during cardiac muscle cell action potential
GO:0086047 IMP membrane depolarization during Purkinje myocyte cell action potential
GO:0086062 IMP voltage-gated sodium channel activity involved in Purkinje myocyte action potential
GO:0086091 IMP regulation of heart rate by cardiac conduction
GO:2000649 IDA regulation of sodium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000098548 Scn1b-001 protein_coding Mus_musculus 0 876
ENSMUST00000188002 Scn1b-004 protein_coding Mus_musculus 0 835
ENSMUST00000187469 Scn1b-003 retained_intron Mus_musculus 0 708

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