ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: TYRO3 protein tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000263798 TYRO3-001 ENSG00000092445 9606 + 15:41559034-41583586 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000263798
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000263798 0.216±0.00 0.413±0.14 0.626±0.00 0.444±0.30

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001779 IEA natural killer cell differentiation
GO:0004672 IEA protein kinase activity
GO:0004713 IEA:IDA protein tyrosine kinase activity
GO:0004714 NAS transmembrane receptor protein tyrosine kinase activity
GO:0004716 NAS receptor signaling protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005635 ISS nuclear envelope
GO:0005789 ISS endoplasmic reticulum membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007155 NAS cell adhesion
GO:0007165 NAS signal transduction
GO:0007283 ISS spermatogenesis
GO:0014065 NAS phosphatidylinositol 3-kinase signaling
GO:0016021 IEA integral component of membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0021885 ISS forebrain cell migration
GO:0023014 NAS signal transduction by phosphorylation
GO:0030168 ISS platelet activation
GO:0032940 ISS secretion by cell
GO:0034122 ISS negative regulation of toll-like receptor signaling pathway
GO:0034446 ISS substrate adhesion-dependent cell spreading
GO:0042698 ISS ovulation cycle
GO:0043277 ISS apoptotic cell clearance
GO:0043491 ISS protein kinase B signaling
GO:0043524 ISS negative regulation of neuron apoptotic process
GO:0043548 IPI phosphatidylinositol 3-kinase binding
GO:0045824 ISS negative regulation of innate immune response
GO:0046777 IDA protein autophosphorylation
GO:0046982 IEA protein heterodimerization activity
GO:0050728 ISS negative regulation of inflammatory response
GO:0051250 IEA negative regulation of lymphocyte activation
GO:0060068 IEA vagina development
GO:0070050 ISS neuron cellular homeostasis
GO:0070527 ISS platelet aggregation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000028763 Tyro3-002 protein_coding Mus_musculus 0 3500
ENSMUST00000110783 Tyro3-001 protein_coding Mus_musculus 0 3400
ENSMUST00000147761 Tyro3-003 retained_intron Mus_musculus 0 1003
ENSMUST00000137135 Tyro3-008 retained_intron Mus_musculus 0 429
ENSMUST00000145380 Ckmt1-003 retained_intron Mus_musculus 0.0000002 64

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