ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: protein kinase, cAMP-dependent, regulatory, type II, beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000265717 PRKAR2B-001 ENSG00000005249 9606 + 7:107044649-107161811 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000265717
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000265717 1.130±0.00 23.814±5.31 16.512±0.00 8.070±4.56

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0001932 IEA regulation of protein phosphorylation
GO:0004862 IDA cAMP-dependent protein kinase inhibitor activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005952 IEA cAMP-dependent protein kinase complex
GO:0006112 TAS energy reserve metabolic process
GO:0006631 IEA fatty acid metabolic process
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007596 TAS blood coagulation
GO:0007612 IEA learning
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0008603 IDA:IEA cAMP-dependent protein kinase regulator activity
GO:0019901 IEA protein kinase binding
GO:0030552 IEA cAMP binding
GO:0031625 IDA ubiquitin protein ligase binding
GO:0034199 TAS activation of protein kinase A activity
GO:0034236 IPI protein kinase A catalytic subunit binding
GO:0035556 TAS intracellular signal transduction
GO:0043197 ISS dendritic spine
GO:0043198 ISS dendritic shaft
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050796 TAS regulation of insulin secretion
GO:0055085 TAS transmembrane transport
GO:0070062 IDA extracellular vesicular exosome
GO:0071377 TAS cellular response to glucagon stimulus
GO:0097546 IEA ciliary base
GO:2000480 IDA negative regulation of cAMP-dependent protein kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000036497 Prkar2b-001 protein_coding Mus_musculus 0 2224
ENSMUST00000003079 Prkar2b-002 protein_coding Mus_musculus 0 1820
ENSMUST00000146865 Prkar2b-003 protein_coding Mus_musculus 0 1714

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