ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: protein kinase C, iota
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000295797 PRKCI-001 ENSG00000163558 9606 + 3:170222365-170305981 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000295797
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000295797 0.331±0.00 4.820±2.63 9.226±0.00 4.564±3.20

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 IEA Golgi membrane
GO:0004672 IDA:IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004697 ISS protein kinase C activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 TAS:IEA ATP binding
GO:0005543 IDA phospholipid binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005829 IDA cytosol
GO:0005886 TAS plasma membrane
GO:0005923 IEA tight junction
GO:0006468 IDA:IEA protein phosphorylation
GO:0006612 NAS protein targeting to membrane
GO:0007010 NAS cytoskeleton organization
GO:0007015 IEA actin filament organization
GO:0008270 IEA zinc ion binding
GO:0010976 IMP positive regulation of neuron projection development
GO:0015630 IDA microtubule cytoskeleton
GO:0016192 TAS vesicle-mediated transport
GO:0016324 IEA apical plasma membrane
GO:0016477 IEA cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019904 IEA protein domain specific binding
GO:0031252 IEA cell leading edge
GO:0032869 ISS cellular response to insulin stimulus
GO:0034329 TAS cell junction assembly
GO:0034351 IMP negative regulation of glial cell apoptotic process
GO:0034613 IEA cellular protein localization
GO:0035089 IEA establishment of apical/basal cell polarity
GO:0035556 IEA intracellular signal transduction
GO:0042462 IEA eye photoreceptor cell development
GO:0043066 TAS negative regulation of apoptotic process
GO:0043220 IEA Schmidt-Lanterman incisure
GO:0043234 IEA protein complex
GO:0043434 IEA response to peptide hormone
GO:0043524 IDA negative regulation of neuron apoptotic process
GO:0045171 IDA intercellular bridge
GO:0045177 IEA apical part of cell
GO:0045197 TAS establishment or maintenance of epithelial cell apical/basal polarity
GO:0045216 IMP cell-cell junction organization
GO:0046326 ISS positive regulation of glucose import
GO:0046903 NAS secretion
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048194 IEA Golgi vesicle budding
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:0060252 IMP positive regulation of glial cell proliferation
GO:0061024 NAS membrane organization
GO:0070062 IDA extracellular vesicular exosome
GO:0070555 IEA response to interleukin-1
GO:0070830 TAS tight junction assembly
GO:0090004 ISS positive regulation of establishment of protein localization to plasma membrane
GO:2000353 IMP positive regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000108249 Prkci-001 protein_coding Mus_musculus 0 2464
ENSDART00000015723 prkci-001 protein_coding Danio_rerio 0 754
ENSMUST00000130238 Prkci-002 protein_coding Mus_musculus 0 673
ENSMUST00000123971 Prkci-003 processed_transcript Mus_musculus 0 667
ENSMUST00000136086 Prkci-005 protein_coding Mus_musculus 0 460
ENSMUST00000130706 Prkci-004 retained_intron Mus_musculus 0 374

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