ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: methyltransferase like 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000298717 METTL3-001 ENSG00000165819 9606 - 14:21498138-21511375 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000298717
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000298717 7.424±0.00 20.708±6.14 16.573±0.00 22.224±8.28

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001510 IMP RNA methylation
GO:0003723 IEA RNA binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006139 IEA nucleobase-containing compound metabolic process
GO:0006397 ISS mRNA processing
GO:0007623 ISS circadian rhythm
GO:0008168 IEA methyltransferase activity
GO:0010467 TAS gene expression
GO:0016422 IMP mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
GO:0016607 IDA nuclear speck
GO:0019827 ISS stem cell maintenance
GO:0036396 IDA MIS complex
GO:0061157 ISS mRNA destabilization
GO:0080009 IMP mRNA methylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022767 Mettl3-001 protein_coding Mus_musculus 0 2383
ENSMUST00000174351 Mettl3-012 nonsense_mediated_decay Mus_musculus 0 1236
ENSMUST00000153539 Mettl3-003 nonsense_mediated_decay Mus_musculus 0 1184
ENSMUST00000147768 Mettl3-002 nonsense_mediated_decay Mus_musculus 0 998
ENSMUST00000173896 Mettl3-014 nonsense_mediated_decay Mus_musculus 0 961
ENSMUST00000122962 Mettl3-004 nonsense_mediated_decay Mus_musculus 0 911
ENSMUST00000174853 Mettl3-009 protein_coding Mus_musculus 0 837
ENSMUST00000156611 Mettl3-005 retained_intron Mus_musculus 0 749
ENSMUST00000127797 Mettl3-006 retained_intron Mus_musculus 0 560
ENSMUST00000173138 Mettl3-015 nonsense_mediated_decay Mus_musculus 0 472
ENSMUST00000173546 Mettl3-010 retained_intron Mus_musculus 0 444
ENSMUST00000174360 Mettl3-013 protein_coding Mus_musculus 0 366
ENSMUST00000130550 Mettl3-008 retained_intron Mus_musculus 0 257
ENSMUST00000145875 Mettl3-007 nonsense_mediated_decay Mus_musculus 0 209
ENSMUST00000173656 Mettl3-011 protein_coding Mus_musculus 0 191
ENSMUST00000022766 Tox4-001 protein_coding Mus_musculus 0 191

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