ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: Rho-associated, coiled-coil containing protein kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000315872 ROCK2-001 ENSG00000134318 9606 - 2:11179761-11344585 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000315872
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000315872 0.380±0.00 3.411±2.79 0.690±0.00 8.190±0.00 3.736±3.04

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000910 NAS cytokinesis
GO:0001843 IEA neural tube closure
GO:0004672 IEA protein kinase activity
GO:0004674 IEA:IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005198 NAS structural molecule activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0006468 IEA:IDA protein phosphorylation
GO:0006939 TAS smooth muscle contraction
GO:0007411 TAS axon guidance
GO:0008625 IEA extrinsic apoptotic signaling pathway via death domain receptors
GO:0010825 IEA positive regulation of centrosome duplication
GO:0016525 IMP negative regulation of angiogenesis
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017048 IEA Rho GTPase binding
GO:0030036 IEA actin cytoskeleton organization
GO:0030155 TAS regulation of cell adhesion
GO:0031616 IEA spindle pole centrosome
GO:0032956 TAS regulation of actin cytoskeleton organization
GO:0035556 IEA intracellular signal transduction
GO:0036464 IDA cytoplasmic ribonucleoprotein granule
GO:0042752 ISS regulation of circadian rhythm
GO:0044822 IDA poly(A) RNA binding
GO:0045616 IMP regulation of keratinocyte differentiation
GO:0046872 IEA metal ion binding
GO:0048511 IEA rhythmic process
GO:0048813 IEA dendrite morphogenesis
GO:0051298 IMP centrosome duplication
GO:0051492 TAS regulation of stress fiber assembly
GO:0051893 TAS regulation of focal adhesion assembly
GO:2000114 TAS regulation of establishment of cell polarity
GO:2000145 TAS regulation of cell motility

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020904 Rock2-201 protein_coding Mus_musculus 0 5729
ENSMUST00000123555 Parp3-004 protein_coding Mus_musculus 0.000000002 71
ENSMUST00000067218 Parp3-001 protein_coding Mus_musculus 0.000000002 71
ENSMUST00000148884 Blzf1-004 retained_intron Mus_musculus 0.00001 58

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