ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: thymidylate synthetase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000323274 TYMS-001 ENSG00000176890 9606 + 18:657604-673578 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000323274
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000323274 25.512±13.68 34.347±26.93 28.193±0.00 30.923±22.68

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000083 TAS regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000166 IEA nucleotide binding
GO:0000278 TAS mitotic cell cycle
GO:0003729 IEA mRNA binding
GO:0004799 TAS:IEA thymidylate synthase activity
GO:0005542 IEA folic acid binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IEA nucleolus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005759 IDA mitochondrial matrix
GO:0005829 TAS cytosol
GO:0006139 TAS nucleobase-containing compound metabolic process
GO:0006206 TAS pyrimidine nucleobase metabolic process
GO:0006231 IEA dTMP biosynthetic process
GO:0006235 IEA dTTP biosynthetic process
GO:0007568 IEA aging
GO:0007623 IEA circadian rhythm
GO:0008144 IEA drug binding
GO:0009157 TAS deoxyribonucleoside monophosphate biosynthetic process
GO:0009636 IEA response to toxic substance
GO:0014070 IEA response to organic cyclic compound
GO:0019088 IEA immortalization of host cell by virus
GO:0019860 IEA uracil metabolic process
GO:0031100 IEA organ regeneration
GO:0032259 IEA methylation
GO:0032570 IEA response to progesterone
GO:0033189 IEA response to vitamin A
GO:0034097 IEA response to cytokine
GO:0042493 IEA response to drug
GO:0042803 IEA protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0045471 IEA response to ethanol
GO:0046078 IEA dUMP metabolic process
GO:0046134 TAS pyrimidine nucleoside biosynthetic process
GO:0046653 IEA tetrahydrofolate metabolic process
GO:0046683 IEP response to organophosphorus
GO:0048037 IEA cofactor binding
GO:0048589 IEA developmental growth
GO:0051216 IEA cartilage development
GO:0051384 IEA response to glucocorticoid
GO:0051593 IEA response to folic acid
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0060574 IEA intestinal epithelial cell maturation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000026846 Tyms-001 protein_coding Mus_musculus 0 1062
ENSMUST00000141630 Tyms-002 nonsense_mediated_decay Mus_musculus 0 782
ENSMUST00000146520 Tyms-010 nonsense_mediated_decay Mus_musculus 0 706
ENSMUST00000134298 Tyms-006 retained_intron Mus_musculus 0 575
ENSMUST00000138520 Tyms-005 processed_transcript Mus_musculus 0 448
ENSMUST00000154751 Tyms-003 retained_intron Mus_musculus 0 243

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