Warning (512): _cake_core_ cache was unable to write 'cake_dev_eng' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'cake_dev_eng'
$value = array(
	'LC_MESSAGES' => array()
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
I18n::translate() - CORE/Cake/I18n/I18n.php, line 237
__d - CORE/Cake/basics.php, line 617
Cache::write() - CORE/Cake/Cache/Cache.php, line 321
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_list'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_list'
$value = array(
	(int) 0 => 'diffexp',
	(int) 1 => 'experiment',
	(int) 2 => 'expressed_transcripts',
	(int) 3 => 'genes',
	(int) 4 => 'go_annotations',
	(int) 5 => 'homologues',
	(int) 6 => 'repeats',
	(int) 7 => 'study',
	(int) 8 => 'synonyms',
	(int) 9 => 'transcripts'
)
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 236
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_transcripts' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_transcripts'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
DataSource::describe() - CORE/Cake/Model/Datasource/DataSource.php, line 135
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 332
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_transcripts' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_transcripts'
$value = array(
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		'collate' => 'latin1_swedish_ci',
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		'default' => null,
		'length' => (int) 32,
		'key' => 'index',
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
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		'null' => true,
		'default' => null,
		'length' => (int) 8,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
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		'length' => (int) 64,
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		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
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		'null' => true,
		'default' => null,
		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
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		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 128,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
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		'null' => false,
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		'length' => (int) 8,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
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)
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
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)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 372
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

• HOME
• GENES
• TRANSCRIPTS
• HELP
• CONTACT

Transcript Info
Description:	hemoglobin, beta
Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
ENST00000335295	HBB-001	ENSG00000244734	9606	-	11:5225464-5227071	protein_coding

Expression Patterns Split around values. Cell Line Name Tissue Condition Heat Map Numeric Values Transcript ID HHSEC ENST00000335295 0.437±0.00

Conserved Regions
Not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0004601	IDA	peroxidase activity
GO:0005344	IEA:NAS	oxygen transporter activity
GO:0005506	IEA	iron ion binding
GO:0005515	IPI	protein binding
GO:0005576	TAS	extracellular region
GO:0005829	TAS	cytosol
GO:0005833	IEA:NAS	hemoglobin complex
GO:0007596	TAS	blood coagulation
GO:0008217	IEA	regulation of blood pressure
GO:0010942	IDA	positive regulation of cell death
GO:0015671	IEA:NAS	oxygen transport
GO:0015701	TAS	bicarbonate transport
GO:0019825	IEA:IDA	oxygen binding
GO:0020037	IEA	heme binding
GO:0030185	NAS	nitric oxide transport
GO:0030492	IDA	hemoglobin binding
GO:0031720	IDA	haptoglobin binding
GO:0031838	IDA	haptoglobin-hemoglobin complex
GO:0042542	IDA	response to hydrogen peroxide
GO:0042744	IDA	hydrogen peroxide catabolic process
GO:0044281	TAS	small molecule metabolic process
GO:0045429	NAS	positive regulation of nitric oxide biosynthetic process
GO:0050880	IEA	regulation of blood vessel size
GO:0051291	IDA	protein heterooligomerization
GO:0055114	IDA	oxidation-reduction process
GO:0070062	IDA	extracellular vesicular exosome
GO:0070293	IMP	renal absorption
GO:0070527	IMP	platelet aggregation
GO:0071682	TAS	endocytic vesicle lumen
GO:0072562	IDA	blood microparticle

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENSMUST00000023934	Hbb-bs-001	protein_coding	Mus_musculus	0	444
ENSMUST00000098192	Hbb-bt-001	protein_coding	Mus_musculus	0	442
ENSMUST00000153218	Hbb-bs-002	protein_coding	Mus_musculus	0	320
ENSMUST00000131960	Hbb-bs-003	retained_intron	Mus_musculus	0	311

Loading

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                ),
                E_USER_WARNING
            );
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$value = array(
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	'FileEngine' => '/var/www/angiogenes/lib/Cake/Cache/Engine/FileEngine.php',
	'CacheEngine' => '/var/www/angiogenes/lib/Cake/Cache/CacheEngine.php',
	'Inflector' => '/var/www/angiogenes/lib/Cake/Utility/Inflector.php',
	'ErrorHandler' => '/var/www/angiogenes/lib/Cake/Error/ErrorHandler.php',
	'CakePlugin' => '/var/www/angiogenes/lib/Cake/Core/CakePlugin.php',
	'CakeLog' => '/var/www/angiogenes/lib/Cake/Log/CakeLog.php',
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	'ObjectCollection' => '/var/www/angiogenes/lib/Cake/Utility/ObjectCollection.php',
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	'Dispatcher' => '/var/www/angiogenes/lib/Cake/Routing/Dispatcher.php',
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	'ClassRegistry' => '/var/www/angiogenes/lib/Cake/Utility/ClassRegistry.php',
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	'Model' => '/var/www/angiogenes/lib/Cake/Model/Model.php',
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	'ConnectionManager' => '/var/www/angiogenes/lib/Cake/Model/ConnectionManager.php',
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	'DataSource' => '/var/www/angiogenes/lib/Cake/Model/Datasource/DataSource.php',
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$config = '_cake_core_'
$settings = array(
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)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
App::shutdown() - CORE/Cake/Core/App.php, line 899
[main] - [internal], line ??

Warning (512): _cake_core_ cache was unable to write 'method_cache' to File cache [CORE/Cake/Cache/Cache.php, line 323]
Code Context
                ),
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			(int) 5 => '`Transcript`.`chromosome`',
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)
$config = '_cake_core_'
$settings = array(
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	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
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)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DboSource::__destruct() - CORE/Cake/Model/Datasource/DboSource.php, line 3539
[main] - [internal], line ??