ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: RAR-related orphan receptor A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000335670 RORA-001 ENSG00000069667 9606 - 15:60488284-61229319 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000335670
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000335670 0.994±1.14 0.184±0.00 0.746±0.52

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001046 IDA core promoter sequence-specific DNA binding
GO:0001222 IPI transcription corepressor binding
GO:0001223 IPI transcription coactivator binding
GO:0001525 IMP angiogenesis
GO:0003677 IDA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IEA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006355 IDA:IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006805 ISS xenobiotic metabolic process
GO:0008134 IPI transcription factor binding
GO:0008142 IDA oxysterol binding
GO:0008270 IEA zinc ion binding
GO:0008589 ISS regulation of smoothened signaling pathway
GO:0010467 TAS gene expression
GO:0010575 IMP positive regulation vascular endothelial growth factor production
GO:0010906 ISS regulation of glucose metabolic process
GO:0019218 ISS regulation of steroid metabolic process
GO:0021930 ISS cerebellar granule cell precursor proliferation
GO:0030522 IDA intracellular receptor signaling pathway
GO:0032922 ISS circadian regulation of gene expression
GO:0036315 IMP cellular response to sterol
GO:0042692 IMP muscle cell differentiation
GO:0042753 ISS positive regulation of circadian rhythm
GO:0043124 IMP negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IDA:IEA sequence-specific DNA binding
GO:0045599 ISS negative regulation of fat cell differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050728 IMP negative regulation of inflammatory response
GO:0060850 ISS regulation of transcription involved in cell fate commitment
GO:0070328 IMP triglyceride homeostasis
GO:0071456 IMP cellular response to hypoxia
GO:0072539 ISS T-helper 17 cell differentiation
GO:0098531 IDA direct ligand regulated sequence-specific DNA binding transcription factor activity
GO:2000188 ISS regulation of cholesterol homeostasis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000034766 Rora-001 protein_coding Mus_musculus 0 2185
ENSMUST00000113624 Rora-002 protein_coding Mus_musculus 0 1925
ENSDART00000121449 roraa-201 protein_coding Danio_rerio 0 889
ENSDART00000148537 roraa-001 protein_coding Danio_rerio 0 889
ENSMUST00000174296 Rora-006 nonsense_mediated_decay Mus_musculus 0 745
ENSMUST00000140351 Rora-003 processed_transcript Mus_musculus 0 220

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