ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: lamin A/C
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000368300 LMNA-001 ENSG00000160789 9606 + 1:156114707-156140089 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000368300
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000368300 194.867±0.00 91.593±42.59 44.085±0.00 63.290±0.00 55.828±41.46

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000278 TAS mitotic cell cycle
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005638 TAS lamin filament
GO:0005652 TAS nuclear lamina
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005882 TAS:IEA intermediate filament
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0006997 IEA nucleus organization
GO:0006998 IEA nuclear envelope organization
GO:0007077 TAS mitotic nuclear envelope disassembly
GO:0007084 TAS mitotic nuclear envelope reassembly
GO:0007517 IMP muscle organ development
GO:0030334 ISS regulation of cell migration
GO:0030951 ISS establishment or maintenance of microtubule cytoskeleton polarity
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0034504 ISS protein localization to nucleus
GO:0035105 IEA sterol regulatory element binding protein import into nucleus
GO:0044267 TAS cellular protein metabolic process
GO:0048471 IDA perinuclear region of cytoplasm
GO:0055015 IEA ventricular cardiac muscle cell development
GO:0071456 IEP cellular response to hypoxia
GO:0090201 IEA negative regulation of release of cytochrome c from mitochondria
GO:0090343 IDA positive regulation of cell aging
GO:1900180 IEA regulation of protein localization to nucleus
GO:2001237 IEA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000029699 Lmna-001 protein_coding Mus_musculus 0 2990
ENSMUST00000120377 Lmna-002 protein_coding Mus_musculus 0 2327
ENSMUST00000036252 Lmna-003 protein_coding Mus_musculus 0 1687
ENSMUST00000135494 Lmna-005 processed_transcript Mus_musculus 0 909
ENSMUST00000149068 Lmna-004 protein_coding Mus_musculus 0 652
ENSMUST00000150496 Lmna-007 retained_intron Mus_musculus 0 409
ENSMUST00000147537 Lmna-006 retained_intron Mus_musculus 0 388

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