ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: dihydropyrimidine dehydrogenase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000370192 DPYD-001 ENSG00000188641 9606 - 1:97077743-97921023 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000370192
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000370192 0.679±0.56 13.675±18.39 1.013±0.00 5.480±0.00 3.480±2.57

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004152 IEA dihydroorotate dehydrogenase activity
GO:0005737 IDA:IEA cytoplasm
GO:0005829 IDA cytosol
GO:0006145 IMP purine nucleobase catabolic process
GO:0006206 TAS pyrimidine nucleobase metabolic process
GO:0006208 ISS pyrimidine nucleobase catabolic process
GO:0006210 IDA thymine catabolic process
GO:0006212 IDA uracil catabolic process
GO:0006214 IDA thymidine catabolic process
GO:0006222 IEA UMP biosynthetic process
GO:0008033 IEA tRNA processing
GO:0016491 IEA oxidoreductase activity
GO:0016627 IEA oxidoreductase activity, acting on the CH-CH group of donors
GO:0017113 ISS dihydropyrimidine dehydrogenase (NADP+) activity
GO:0017150 IEA tRNA dihydrouridine synthase activity
GO:0019483 IEA beta-alanine biosynthetic process
GO:0042803 ISS protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0046135 TAS pyrimidine nucleoside catabolic process
GO:0046872 IEA metal ion binding
GO:0050660 ISS:IEA flavin adenine dinucleotide binding
GO:0050661 ISS NADP binding
GO:0051536 IEA iron-sulfur cluster binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000039177 Dpyd-001 protein_coding Mus_musculus 0 3406
ENSMUST00000126254 Dpyd-003 retained_intron Mus_musculus 0 778
ENSMUST00000150950 Dpyd-002 retained_intron Mus_musculus 0 566
ENSMUST00000129148 Dpyd-005 retained_intron Mus_musculus 0 366
ENSMUST00000149101 Dpyd-004 protein_coding Mus_musculus 0 291

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