ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: growth differentiation factor 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000374372 GDF5-001 ENSG00000125965 9606 - 20:35433347-35454746 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000374372
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000374372 0.432±0.00 0.083±0.03 0.049±0.00 0.107±0.00 0.086±0.05

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002062 IEA chondrocyte differentiation
GO:0005102 IEA receptor binding
GO:0005125 IEA cytokine activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0005886 IEA plasma membrane
GO:0007178 IEA transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0008083 IEA growth factor activity
GO:0030198 TAS extracellular matrix organization
GO:0030326 IEA embryonic limb morphogenesis
GO:0032332 IEA positive regulation of chondrocyte differentiation
GO:0035136 IEA forelimb morphogenesis
GO:0035137 IEA hindlimb morphogenesis
GO:0040007 IEA growth
GO:0040014 IEA regulation of multicellular organism growth
GO:0042802 IPI identical protein binding
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045666 IEA positive regulation of neuron differentiation
GO:0050680 IDA negative regulation of epithelial cell proliferation
GO:2001054 IEA negative regulation of mesenchymal cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000040162 Gdf5-001 protein_coding Mus_musculus 0 2292
ENSMUST00000109629 Gm15557-001 protein_coding Mus_musculus 0 1260

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