ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000377346 PIK3CD-001 ENSG00000171608 9606 + 1:9651745-9728919 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HUVECENST00000377346
Transcript ID HUVEC
ENST00000377346 1.142±0.94

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001779 TAS natural killer cell differentiation
GO:0001782 IEA B cell homeostasis
GO:0001816 TAS cytokine production
GO:0002250 TAS adaptive immune response
GO:0002551 TAS mast cell chemotaxis
GO:0002679 TAS respiratory burst involved in defense response
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005942 NAS phosphatidylinositol 3-kinase complex
GO:0006468 NAS protein phosphorylation
GO:0006644 TAS phospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0006954 TAS inflammatory response
GO:0007165 NAS signal transduction
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0010818 TAS T cell chemotaxis
GO:0014065 TAS phosphatidylinositol 3-kinase signaling
GO:0016303 NAS 1-phosphatidylinositol-3-kinase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0030101 TAS natural killer cell activation
GO:0030217 TAS T cell differentiation
GO:0030593 TAS neutrophil chemotaxis
GO:0035004 TAS phosphatidylinositol 3-kinase activity
GO:0035005 IBA 1-phosphatidylinositol-4-phosphate 3-kinase activity
GO:0035747 TAS natural killer cell chemotaxis
GO:0035754 TAS B cell chemotaxis
GO:0036092 NAS phosphatidylinositol-3-phosphate biosynthetic process
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042110 TAS T cell activation
GO:0042113 TAS B cell activation
GO:0042629 TAS mast cell granule
GO:0043303 TAS mast cell degranulation
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0046854 IEA phosphatidylinositol phosphorylation
GO:0046934 IBA phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0050852 TAS T cell receptor signaling pathway
GO:0050853 TAS B cell receptor signaling pathway
GO:0060374 TAS mast cell differentiation
GO:0072672 TAS neutrophil extravasation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000105688 Pik3cd-013 protein_coding Mus_musculus 0 3860
ENSMUST00000038859 Pik3cd-003 protein_coding Mus_musculus 0 3853
ENSMUST00000177654 Pik3cd-201 protein_coding Mus_musculus 0 3819
ENSMUST00000105690 Pik3cd-001 protein_coding Mus_musculus 0 3819
ENSMUST00000118704 Pik3cd-007 protein_coding Mus_musculus 0 3799
ENSMUST00000122059 Pik3cd-012 protein_coding Mus_musculus 0 3794
ENSMUST00000105689 Pik3cd-002 protein_coding Mus_musculus 0 3792
ENSMUST00000127273 Pik3cd-005 protein_coding Mus_musculus 0 673
ENSMUST00000131224 Pik3cd-004 protein_coding Mus_musculus 0 595
ENSMUST00000146612 Pik3cd-009 protein_coding Mus_musculus 0 518
ENSMUST00000136965 Pik3cb-002 nonsense_mediated_decay Mus_musculus 0 361
ENSMUST00000035037 Pik3cb-001 protein_coding Mus_musculus 0 361
ENSMUST00000134534 Pik3cd-010 protein_coding Mus_musculus 0 324
ENSMUST00000156309 Pik3cd-011 protein_coding Mus_musculus 0 207
ENSMUST00000173269 Neu1-002 retained_intron Mus_musculus 0.000002 60

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